Electrochemical synthesis of selenyl-dihydrofurans via anodic selenofunctionalization of allyl-naphthol/phenol derivatives and their anti-Alzheimer activity

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dc.creatorScheide Neto, Marcos Roberto
dc.creatorSchneider, Alex Ricardo
dc.creatorMartins, Guilherme Ariel Machado
dc.creatorMartins, Guilherme M.
dc.creatorSaba, Sumbal
dc.creatorKhan, Jamal Rafique
dc.creatorBraga, Antonio Luiz
dc.date.accessioned2024-11-07T17:23:53Z
dc.date.available2024-11-07T17:23:53Z
dc.date.issued2020
dc.description.abstractHerein, we report an eco-friendly, electrosynthetic approach for the intramolecular oxyselenylation of allyl-naphthol/phenol derivatives. This reaction proceeds with 0.2 equiv. of nBu4NClO4 as an electrolyte and Pt working electrodes in an undivided cell, resulting in the selenyl-dihydrofurans in good to excellent yields. Furthermore, several of the synthesized products presented a high percentage of acetylcholinesterase (AChE) inhibition, highlighting their potential anti-Alzheimer activity.
dc.identifier.citationSCHEIDE NETO, Marcos Roberto et al. Electrochemical synthesis of selenyl-dihydrofurans via anodic selenofunctionalization of allyl-naphthol/phenol derivatives and their anti-Alzheimer activity. Organic & Biomolecular Chemistry, v. 18, n. 26, p. 4916-4921, 2020. DOI: 10.1039/D0OB00629G. Disponível em: https://pubs.rsc.org/en/content/articlelanding/2020/ob/d0ob00629g. Acesso em: 31 jul. 2024.
dc.identifier.doi10.1039/D0OB00629G
dc.identifier.doihttps://pubs.rsc.org/en/content/articlelanding/2020/ob/d0ob00629g
dc.identifier.issne- 1477-0539
dc.language.isoeng
dc.publisher.countryGra-bretanha
dc.publisher.departmentInstituto de Química - IQ (RMG)
dc.rightsAcesso Restrito
dc.titleElectrochemical synthesis of selenyl-dihydrofurans via anodic selenofunctionalization of allyl-naphthol/phenol derivatives and their anti-Alzheimer activity
dc.typeArtigo

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