A revisão rápida de 100% é eficiente na detecção de resultados falsos-negativos dos exames citopatológicos cervicais e varia com a adequabilidade da amostra: uma experiência no Brasil
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Data
2007
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Resumo
PURPOSE: to evaluate the effi ciency of the 100% rapid rescreening in the detection of false-negative results and to verify
whether the results vary according to the adequacy of the sample and the woman’s age group. METHODS: to evaluate
the effi ciency of the rapid rescreening, the 5,530 smears classifi ed as negative by the routine screening, after being
submitted to the rapid rescreening of 100%, were compared with the rescreening of the smears on the basis of clinical
criteria and 10% random rescreening. For statistical analysis, the variables were evaluated descriptively and the χ 2 test
and the Cochran-Armitage test were applied to compare results. RESULTS: of the 141 smears identifi ed as suspicious
according to the rapid rescreening method, 84 (59.6%) cases were confi rmed in the fi nal diagnosis, of which 36 (25.5%)
were classifi ed as atypical squamous cells of undetermined signifi cance, fi ve (3.5%) as atypical squamous cells that cannot
exclude high-grade squamous intraepithelial lesion, 34 (24.1%) as low-grade squamous intraepithelial lesion, six (4.3%)
as high-grade squamous intraepithelial lesion, and three (2.1%) as atypical glandular cells. Of the 84 suspect smears
confi rmed in the fi nal diagnosis, 62 (73.8%) smears were classifi ed as adequate and 22 (26.2%) as adequate but with
some limitation, but no signifi cant difference was observed with the woman’s age. CONCLUSIONS: the results of this
study show that rapid rescreening is an effi cient option for internal quality control for the detection of false-negative cervical
smear results. In addition, it should be noted that rapid rescreening performed better when the sample was classifi ed as
adequate for analysis; however, it did not vary according to the woman’s age group.
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Neoplasias do colo do útero/ diagnóstico C, Citodiagnóstico, Reações falso-negativas, Programas de rastreamento, Controle de qualidade, Garantia da qualidade dos cuidados de saúde/método, Uterine cervical neoplasms/diagnosis, Cytodiagnosis, False negative reactions, Mass screening, Quality control, Quality assurance, health care/ methods
Citação
MANRIQUE, Edna Joana Cláudio; TAVARES, Suelene Brito Do Nascimento; Souza, Nadja Lindany Alves; Albuquerque, Zair Benedita Pinheiro; ZEFERINO, Luiz Carlos; AMARAL, Rita Goreti. A revisão rápida de 100% é eficiente na detecção de resultados falsos-negativos dos exames citopatológicos cervicais e varia com a adequabilidade da amostra: uma experiência no Brasil. Revista Brasileira de Ginecologia e Obstetrícia, São Paulo, v. 29, n. 8, p. 402-407, 2007.