A revisão rápida de 100% é eficiente na detecção de resultados falsos-negativos dos exames citopatológicos cervicais e varia com a adequabilidade da amostra: uma experiência no Brasil

Resumo

PURPOSE: to evaluate the effi ciency of the 100% rapid rescreening in the detection of false-negative results and to verify whether the results vary according to the adequacy of the sample and the woman’s age group. METHODS: to evaluate the effi ciency of the rapid rescreening, the 5,530 smears classifi ed as negative by the routine screening, after being submitted to the rapid rescreening of 100%, were compared with the rescreening of the smears on the basis of clinical criteria and 10% random rescreening. For statistical analysis, the variables were evaluated descriptively and the χ 2 test and the Cochran-Armitage test were applied to compare results. RESULTS: of the 141 smears identifi ed as suspicious according to the rapid rescreening method, 84 (59.6%) cases were confi rmed in the fi nal diagnosis, of which 36 (25.5%) were classifi ed as atypical squamous cells of undetermined signifi cance, fi ve (3.5%) as atypical squamous cells that cannot exclude high-grade squamous intraepithelial lesion, 34 (24.1%) as low-grade squamous intraepithelial lesion, six (4.3%) as high-grade squamous intraepithelial lesion, and three (2.1%) as atypical glandular cells. Of the 84 suspect smears confi rmed in the fi nal diagnosis, 62 (73.8%) smears were classifi ed as adequate and 22 (26.2%) as adequate but with some limitation, but no signifi cant difference was observed with the woman’s age. CONCLUSIONS: the results of this study show that rapid rescreening is an effi cient option for internal quality control for the detection of false-negative cervical smear results. In addition, it should be noted that rapid rescreening performed better when the sample was classifi ed as adequate for analysis; however, it did not vary according to the woman’s age group.

Descrição

Palavras-chave

Neoplasias do colo do útero/ diagnóstico C, Citodiagnóstico, Reações falso-negativas, Programas de rastreamento, Controle de qualidade, Garantia da qualidade dos cuidados de saúde/método, Uterine cervical neoplasms/diagnosis, Cytodiagnosis, False negative reactions, Mass screening, Quality control, Quality assurance, health care/ methods

Citação

MANRIQUE, Edna Joana Cláudio; TAVARES, Suelene Brito Do Nascimento; Souza, Nadja Lindany Alves; Albuquerque, Zair Benedita Pinheiro; ZEFERINO, Luiz Carlos; AMARAL, Rita Goreti. A revisão rápida de 100% é eficiente na detecção de resultados falsos-negativos dos exames citopatológicos cervicais e varia com a adequabilidade da amostra: uma experiência no Brasil. Revista Brasileira de Ginecologia e Obstetrícia, São Paulo, v. 29, n. 8, p. 402-407, 2007.