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    A graduação médica e a prática profissional na perspectiva de discentes
    (2013) Filisbino, Marcos Augusto; Moraes, Vardeli Alves de
    Introduction: The aim of this research is to identify, in terms of professional practice, the ideal internship students in the Medical School of the Federal University of Goiás (UFG) and to observe possible dissonances in relation to the graduate profile as advocated by the National Curriculum Guidelines and by the Political Pedagogical Project of this institution. Methods: In 2012, two hundred and twenty-two medical internship students of the institution received a survey questionnaire. The sample of this research consisted of one hundred and ninety research subjects, representing 85% of the sample universe. The statistical significance was calculated using the Sign Test. Results: The socio-demographic profile characterizes the students with an average age of 23.8 years old, unmarried, 66% of whom belong to social classes A and B. The ideal profile of professional practice shows that 84% want to become specialists, whereas 96% want to engage in medical residency, which is statistically significant (p = 0.0001), and 70% do not intend to work with Family Health Strategy Programs (p = 0.005). Conclusion: This study shows that students with high socio-economic profile, who want to become specialists, undergo a medical residency program and do not see the Family Health Strategy as a professional goal.
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    Soroprevalência do virus hepatite C na população em diálise de Goiania-GO
    (1997-04) Naghettini, Alessandra Vitorino; Daher, Roberto Ruhman; Martins, Regina Maria Bringel; Vanderborght, Bart; Yoshida, Clara Fumiko Tachiban
    A cross-sectional study was performed to determine the prevalence of HCV among dialysis population in Goiânia and its association with possible risk factors. The patients were 173, aged 10 to 70 years old. An Elisa II test was undertaken and 61 of 173 (35.3%) had positive test; when INNO-LIA test was made, soropositivity was 26% (44/173). Patients with anti-VHC antibodies have been kept on hemodialysis treatment for periods longer than negatives (p < 0.05). Neither drugs users, blood transfusions, sexual and aminotransferase activity were significantly correlated with the infection. There is an elevated prevalence of anti-VHC antibodies among chronic hemodialysis patients which seems to be related to the time that patients are on dialysis treatment.
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    Decline of hepatitis C infection in hemodialysis patients in Central Brazil: a ten years of surveillance
    (2005-07) Carneiro, Megmar Aparecida dos Santos; Teles, Sheila Araujo; Matos, Márcia Alves Dias de; Souto, Renata Carneiro Ferreira; Naghettine, Alessandra Vitorino; Silva, Simonne Almeida e; Lampe, Elisabeth; Yoshida, Clara Fumiko Tachibana; Martins, Regina Maria Bringel
    Hepatitis C virus (HCV) has been a significant problem for hemodialysis patients. However this infection has declined in regions where the screening for anti-HCV in blood banks and hemodialysis-specific infection control measures were adopted. In Brazil, these measures were implemented in 1993 and 1996, respectively. In addition, all studied units have implemented isolation of anti-HCV positive patients since 2000. In order to evaluate the impact of these policies in the HCV infection prevalence, accumulated incidence, and risk factors in hemodialysis population of Goiânia City, Central Brazil, all patients were interviewed and serum samples tested for HCV antibodies in 1993, 1996, 1999, and 2002. In the first six years (1993-1999), anti-HCV prevalence increased from 28.2 to 37.2%, however a strong decrease in positivity was detected between 1999 and 2002 (37.8 vs 16.5%) when the measures were fully implemented. Also, a decrease of the anti-HCV accumulated incidence in cohorts of susceptible individuals during 1993-2002 (71%), 1996-2002 (34.2%), and 1999-2002 (11.7%) was found. Analysis of risk factors showed that length of time on hemodialysis, blood transfusion before screening for anti-HCV and treatment in multiple units were statistically associated with anti-HCV (p < 0.05). Our study showed a significant decline of hepatitis C infection in hemodialysis patients of Central Brazil, ratifying the importance of public health strategies for control and prevention of hepatitis C in the hemodialysis units.
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    Avaliação dos fatores de risco e proteção associados à elevação da pressão arterial em crianças
    (2010) Naghettini, Alessandra Vitorino; Belem, Joice Moraes Faria Monteiro; Salgado, Cláudia Maria; Vasconcelos Junior, Huber Martins; Seronni, Elaine Maria Xavier; Junqueira, Ana Luiza Neto; Fortes, Patricia Marques
    Background: Epidemiological studies have shown an increased prevalence of high blood pressure in pediatric patients. Today we know that risk factors can be detected during childhood and may help in preventing the disease. Objective: To evaluate risk and protection factors related to high blood pressure in childhood. Methods: We evaluated children aged 3 to10 years, residing in the east and southwest sanitary districts of the City of Goiânia, Goiás, and obtained the following data: birth weight, breastfeeding, family history of high blood pressure and obesity, weight, height, body mass index (BMI), and blood pressure. We applied the Mann-Whitney U-test to these variables in order to compare pressure variation. Results: In this sample, 519 children were evaluated, and 246 (47.4%) of them were male. The BMI assessment identified 109 (21%) overweight children, of which 53 (10.3%) were obese. Predominant and/or exclusive breastfeeding for less than 6 months was found in 242 (51.2%). The mean systolic pressure was significantly higher in children with exclusive and/or predominant breastfeeding for less than 6 months (p = 0.04), and in children with family history of high blood pressure (p = 0.05), and in overweight children (p <0.0001). These data were confirmed in multivariate analysis. Conclusion: In this sample, we observed that overweight and hereditary factors may be associated with elevated blood pressure, and that breastfeeding for more than 6 months seems to offer a protective effect. (Arq Bras Cardiol. 2010; [online]. ahead print, PP.0-0)
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    Identificando fatores de risco para desenvolvimento de doença renal crônica entre escolares
    (2012) Naghettini, Alessandra Vitorino; Salgado, Cláudia Maria; Freitas, Jonathan Santana; Salgado, Luciana Martins Rodrigues
    Aiming at identifying risk factors for chronic kidney disease (CKD) among schoolchildren, a cross-sectional population study was carried out in six municipal schools in Goiânia, Brazil. We investigated: history of birthweight, enuresis, urinary incontinence, mictional urgency, family history of kidney disease, diabetes, arterial hypertension, percentiles of arterial blood pressure, waist circumference and body mass index (BMI). We evaluated 274 children, mean age of 8.06 ± 1.33 years, among which 139 (50.7%) were female. We detected: enuresis in 50 (18.2%); urinary incontinence in 34 (12.4%); mictional urgency in 49 (17.9%); BMI above P85 in 18.8% (45); waist circumference above P90 in 17 (6.9%); arterial blood pressure above P95 in 17 (7.1%). Also, we observed correlation between arterial blood pressure, obesity, and increased waist circumference, (p < 0.05). The study showed high frequency of abnormal voiding habits and increased BMI in this population.
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    Quebrando barreiras: integração do currículo de pediatria a partir da criação de uma matriz de competências
    (2011) Naghettini, Alessandra Vitorino; Bollela, Valdes Roberto; Costa, Nilce Maria da Silva Campos; Salgado, Luciana Martins Rodrigues
    Objective: To describe the process of integration and revision of a pediatric program curriculum which resulted in the creation of a competency-based framework recommended in the Brazilian National Curricular Guidelines. Methods: Quali-quantitative analysis of an intervention evaluating the students and professors’ perception of the pediatric program curriculum (focus groups and semi-structured interviews). Results were discussed during teaching development workshops. A competency-based framework was suggested for the pediatric program from the 3rd to the 6th year. The new curriculum was approved, implemented, and reevaluated six months later. Results: Twelve students (12%) from the 3rd to the 6th year participated in the focus groups, and 11 professors (78.5%) answered the questionnaire. Most participants reported lack of integration among the courses, lack of knowledge about the learning goals of the internships, few opportunities of practice, and predominance of theoretical evaluation. In the training workshops, a competency-based curriculum was created after pediatrics and collective health professors reached an agreement. The new curriculum was focused on general competency, learning goals, opportunities available to learn these goals, and evaluation system. After six months, 93% (104/112) of students and 79% (11/14) of professors reported greater integration of the program and highlighted the inclusion of the clinical performance evaluation. Conclusion: The collective creation of a competency-based curriculum promoted higher satisfaction of students and professors. After being implemented, the new curriculum was considered to integrate the teaching practices and contents, improving the quality of the clinical performance evaluation.
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    Tubular urinary enzymes in acute post-infectious glomerulonephritis
    (2001) Naghettini, Alessandra Vitorino; Nogueira, Paulo Cesar Koch; Juliano, Maria Ligia; Bueno, Allain Amador; Casarini, Dulce Elena; Carvalhães, João Tomás de Abreu
    Tubular function of 17 pediatric patients with a mild form of acute post-infectious glomerulonephritis was prospectively evaluated by assessment of the urinary activity of proximal and distal tubule enzymes. Neutrallike endopeptidase (NEP-like) and angiotensin-converting enzyme (ACE) were the proximal tubule enzymes assessed, while prolyl-endopeptidase (PE) and serine-endopeptidase H1 and H2 were the distal tubule enzymes analyzed. Urine was collected at diagnosis (T0) and after 2 (T2) and 6 (T6) months of follow-up. NEP-like enzyme activity (nmol/mg creatinine; median±quartile range) was increased at diagnosis, and this remained stable during the first 6 months (T0 18.30±83.26, T2 17.32±49.56, T6 23.38±107.18). Urinary activity of the other enzymes was as follows: ACE (mU/ml per mg creatinine) T0 0.08±0.16, T2 0.06±0.10, T6 0.18±0.29; PE (nmol/mg creatinine) T0 6.70±84.87, T2 9.55±69.00, T6 13.67±28.70; serine-endopeptidase H1 (nmol/mg creatinine) T0 7.86±26.95, T2 17.17±59.37, T6 18.19± 79.14; and serine-thiol-endopeptidase H2 (nmol/mg creatinine) T0 3.06±21.97, T2 12.06±32.42, T6 16.22± 44.06. Thirty other healthy children matched for age and gender were considered as a control group. This group was assessed once and the results were: NEP-like activity 6.05±10.54, ACE 0.11±0.22, PE 7.10±13.36, H1 5.00±17.30, and H2 6.00±20.16. In conclusion, we observed that NEP-like and H1 enzymes exhibited significant increased urinary activity 6 months after the diagnosis. This increase occurred in spite of the disappearance of clinical symptoms, which occurred 2 months after the diagnosis. We believe that the increase in urinary enzymatic activity could be a manifestation of a silent tubular dysfunction following an episode of acute post-infectious glomerulonephritis.
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    Competências da preceptoria na residência médica
    (2013-10) Santos, Alex Caetano dos; Moraes, Alexandre Vieira Santos; Costa, Ana Carolina Arantes Coutinho; Lima, Beatriz Lins Galvão de; Vieira, Carlos Alberto Lisboa; Viggiano, Daniela Pultrini Pereira de Oliveira; Carvalho, Gelcio Sisteroli de; Matos Filho, Gilberto de; Fonseca, Gisele Rodrigues; NaghettiniI, Alessandra Vitorino
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    Conhecimento sobre doença pulmonar obstrutiva crônica em pacientes de diferentes níveis de atividade física
    (Universidade Federal de Goiás, 2020-07-17) Souza, Hortência Vilione Pereira de; Garcia, Rejanny Duque Thomaz; Rabahi, Marcelo Fouad; Corrêa, Krislainy de Sousa
    The aim of this study was to identify and compare the level of knowledge about chronic obstructive pulmonary disease in active, sedentary and severely inactive individuals. This is a cross-sectional study with individuals with chronic obstructive pulmonary disease. A clinical evaluation form, the Bristol COPD Knowledge Questionnaire, and pedometers (step counter) were used for data collection. Of the 75 individuals evaluated, 70.7% were severely inactive. There was a low level of knowledge about chronic obstructive pulmonary disease (48.51 ± 9.08%), and it was found that active, sedentary and severely inactive individuals have a similar level of knowledge about the disease (50.19 ± 11.18% vs 46.48 ± 8.16% vs 48.79 ± 9.06%, p=0.68). It is concluded, therefore, that individuals with active, sedentary and severely inactive chronic obstructive pulmonary disease have similar and reduced knowledge about the disease.
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    Eu te respeito, você me respeita: incentivando o uso de máscaras caseiras
    (Universidade Federal de Goiás, 2021-12-27) Rabahi, Marcelo Fouad; Novaes, Maristela Abadia Fernandes; Rufino, João Pedro
    The new coronavirus (SARS-CoV-2) is transmitted via respiratory droplets and the use of simple facial masks that exercise a barrier function that blocks the large projectile droplets that reach the nose or throat. The proposed action focused on the use of homemade facial masks as a symbol of respect and solidarity, fundamental feelings for facing COVID-19. Digital means were used to disseminate scientific information and encourage the use of masks, in addition to proposing models and prototypes of masks development through UFG’s Instagram posts. The action received the engagement of 2436 individuals. The university, by occupying the media, has contributed to reducing the risk of inappropriate attitudes on the part of those who receive the information. The COVID-19 pandemic will have profound repercussions on social life. The university must assume its social responsibility to produce knowledge, translate it and promote it among the community.
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    Tratamento não medicamentoso e abordagem multiprofissional
    (2010) Malachias, Marcus Vinícius Bolívar; Souza, Weimar Kunz Sebba Barroso de; Lottenberg, Ana Maria Pita; Guimarães, Armênio Costa; Negrão, Carlos Eduardo; Forjaz, Claudia Lucia de Moraes; Lopes, Heno Ferreira; Santos, José Ernesto dos; Ângelo, Luciana Ferreira; Correia, Marcelo Lima de Gusmao
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    V Diretrizes de MAPA e III de MRPA
    (2011) Nobre, Fernando; Gomes, Marco Antônio Mota; Brandão, Andréa Araujo; Feitosa, Audes Diógenes de Magalhães; Figueiredo, Carlos Eduardo Poli de; Rodrigues, Cibele Isaac Saad; Plavnik, Frida Liane; Silva Neto, João David da; Barbosa, Jose Bonifácio; Souza, Weimar Kunz Sebba Barroso de
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    Análise de eficácia, eventos adversos e desfechos cardiovasculares em estudos relacionados às combinações de nifedipino GITS ou anlodipino com medicamentos que atuam no sistema renina angiotensina aldosterona
    (2013) Oliveira Junior, Francisco Vitor de; Souza, Weimar Kunz Sebba Barroso de
    We reviewed 17 studies in order to evaluate the antihypertensive efficacy on the combination of calcium antagonists and angiotensin receptor blockers in lowering the blood pressure, cardiovascular outcomes and incidence of side effects. The combination therapy of amlodipine or nifedipine GITS calcium channel blockers, and angiotensin II receptor blocker valsartan showed, in most studies, more effective than monotherapy to lower blood pressure, as well as more beneficial to decrease cardiovascular events. The safety profile and tolerability of the combinations also proved quite acceptable, with side effects management benefited by higher possibility of adjustments on doses of substances with different mechanisms of actions, without affecting the antihypertensive efficacy.
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    I posicionamento brasileiro sobre combinação de fármacos anti-hipertensivos
    (2014) Póvoa, Rui Manuel dos Santos; Souza, Weimar Kunz Sebba Barroso de; Brandão, Andréa Araujo; Jardim, Paulo Cesar Brandao Veiga; Souza, Oswaldo Kunz Sebba Barroso de; Passarelli Júnior, Oswaldo; Gemelli, João Roberto; Feitosa, Audes Diógenes de Magalhães; Jardim, Thiago de Souza Veiga; Carneiro, Sergio Baiocchi
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    Qual(ais) o(s) antagonistas dos canais de cálcio mais indicado(s) no tratamento da hipertensão arterial?
    (2013) Jardim, Paulo César Brandão Veiga; Jardim, Thiago de Souza Veiga; Souza, Weimar Kunz Sebba Barroso de
    Pharmacological treatment of high blood pressure can begin with any of the five main group of antihypertensive drugs (diuretics, ace inhibitors, angiotensin receptors blockers, calcium channel blockers and betablockers). Among these, calcium channel blockers reduce blood pressure mainly by decreasing periphereal vascular resistance. They are divided in two subgroups: non dihydropyridines (benzothiazepines and fenilalquilaminas) and dihydropyridines. In the first subgroup are included Verapamil and Diltiazem respectively, and in the second Nifedipine, Felodipine, Isradipine, Nitrendipine, Anlodipine, Lacidipine, Lercanidipine, Manidipine e Levanlodipine. In high blood pressure treatment only those with long term action should be used. The drugs from the first subgroup have additional action at the miocardium and should be used with caution. The most usuals side effects of the calcium channel blockers are due to periphereal vasodilation (headache, flushing and dizziness) and other side effect often seen is malleolar edema wich can limit its use and is not caused by fluid retention. There are several evidences from randomized clinical trials, meta-analysis e sistematic reviews, of the benefits that these drugs lead in reducing blood pressure and cardiovascular events both in monotherapy or in association with other antihypertensive drug. The choice between wich calcium channel blocker to be used should be made considering the patient characteristics, therapeutic efficacy, action duration, tolerability and clinical experience.
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    I posicionamento brasileiro em hipertensão arterial e diabetes mellitus
    (2013) Souza, Weimar Kunz Sebba Barroso de; Póvoa, Rui Manuel dos Santos; Brandão, Andrea Araujo; Barbosa, Eduardo; Alessi, Alexandre; Carneiro, Sérgio Baiocchi; Jardim, Paulo Cesar Veiga; Jardim, Thiago; Franco, Roberto; Martin, Luis C.
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    Incidência de arritmias ventriculares após terapia celular em pacientes com cardiomiopatia chagásica
    (2014) Souza, Adriana Sebba Barroso de; Souza, Weimar Kunz Sebba Barroso; Costa, Sandra de Araujo; Freitas, Elis Marra de Moreira; Carvalho, Gustavo; Sá, Luís Antônio Batista; Rassi, Salvador
    Background: Treatment with stem cells in several cardiomyopathies may be related to the increase in arrhythmias. Objectives: To determine whether intracoronary injection of stem cells in patients with Chagas cardiomyopathy is associated with increased incidence of ventricular arrhythmias, compared to the Control Group. Methods: A retrospective cohort study that evaluated the medical records of 60 patients who participated in a previous cross-sectional study. The following data were collected: age, gender, drugs used and Holter variables that demonstrated the presence of arrhythmias. Holter was performed in four stages: randomization, 2, 6 and 12 months segments. The Control Group received medical treatment and intracoronary injection of placebo and the Study Group had drug treatment and autologous stem cell implant. Results: There was no difference between Control Group and Study Group when analyzing the arrhythmia criteria. In the intra-group analysis, significant difference was found between the Holter tests of the Study Group for the variable total ventricular premature beats when compared with baseline, with p = 0.014 between Holter at randomization and Holter at 2 months, p = 0.004 between Holter at randomization and Holter at 6 months, and p = 0.014 between Holter at randomization and Holter at 12 months. The variable non-sustained ventricular tachycardia between Holter at randomization and Holter at 6 months showed p = 0.036. Conclusion: The intracoronary injection of stem cells did not increase the incidence of ventricular arrhythmias in patients with Chagas cardiomyopathy compared to the Control Group.
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    Profile pressure between hypertensive with and without diabetes
    (2015) Sousa, Andréa Cristina de; Souza, Haroldo Silva de; Costa, Thiago Oliveira; Montelo, Marcos Paulo Marinho; Arantes, Ana Carolina; Araujo, Ymara Cássia Luciana; Rodrigues, Rafaela Bernardes; Oliveira, Simone Dias Souza de; Moreira, Humberto Graner; Pereira, Dalma Alves; Oliveira, Camila Ferreira de; Jardim, Thiago de Souza Veiga; Euzébio, Maicon Borges; Souza, Weimar Kunz Sebba Barroso de; Jardim, Paulo Cesar Brandão Veiga; Sousa, Ana Luiza Lima
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    Ginástica tradicional e gravidez
    (2009) Melo, Marisa Guimaraes de; Amaral, Waldemar Naves do
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    Ultrassonografia nas patologias miometriais
    (2010-06) Nascimento, Dalva Marcelino Furtado do; Amaral, Waldemar Naves do; Amaral Filho, Waldemar Naves do