Ineffectiveness of antibiotic-based pulpotomy for primary molars: a survival analysis
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Data
2015
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Resumo
Objective: To investigate the two-year survival rate of primary molars treated with
non-instrumentation endodontic treatment with mixed antibiotic paste containing
chloramphenicol, tetracycline, zinc oxide and eugenol (CTZ pulpotomy), and compare it
to the conventional root canal treatment with calcium hydroxide paste. Material and
Methods: Thirty-six children, mean age 6.2 years old (standard deviation, SD=1.5),
presenting at least one primary molar with irreversible pulpitis or necrotic pulp, were
included in this prospective clinical study. Teeth were assigned to CTZ pulpotomy
(Group I) or calcium hydroxide pulpectomy (Group II) and assessed clinically and
radiographically for up to 26 months. Data were analyzed using descriptive statistics,
Chi-square test, Kaplan-Meier survival analysis and Log-rank test. Results: Fifty-three
primary molars were treated in Group I (n=37) or Group II (n=16). Children were
followed up for 1 to 26 months (mean=12.0; SD=7.1). Treatment failure rates were
73.0% in Group I and 31.3% in Group II. Overall, mean survival time was 15.2 months
(95% confidence interval, CI 12.6–17.9); Group I (mean 13.2; 95% CI 10.2-16.3) had a
lower survival rate than Group II (mean 18.9; 95% CI 14.5-23.2) (p=0.02). Necrotic pulp
treatments had significantly lower survival rates (p=0.01) than pulpitis treatments.
Conclusion: Non-instrumentation endodontic treatment of primary molars with CTZ
paste resulted in a low survival rate in a two-year follow-up; its radiographic
ineffectiveness discourages its use instead of conventional root canal endodontic
treatment.
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Anti-bacterial agents, Root canal therapy, Tooth, Deciduous, Pulpotomy
Citação
DAHER, Anelise et al. Ineffectiveness of antibiotic-based pulpotomy for primary molars: a survival analysis. Pesquisa Brasileira em Odontopediatria e Clínica Integrada, Campina Grande, v. 15, n. 1, p. 205-215, 2015.