Atividade antiproliferativa de Sloanea garckeana K. Schum

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dc.creatorRomero, Adriano Lopes
dc.creatorFontana, Álvaro
dc.creatorSilva, Cleuza Conceição da
dc.creatorSouza, Maria Conceição de
dc.creatorCarvalho, João Ernesto de
dc.creatorFaria, Emiret Otoni de
dc.creatorKato, Lucilia
dc.creatorOliveira, Cecília Maria Alves de
dc.date.accessioned2018-06-27T12:37:27Z
dc.date.available2018-06-27T12:37:27Z
dc.date.issued2008
dc.description.abstractThe crude methanol extract and hexane, ethyl acetate, chloroform and methanol fractions from leaves of S. garckeana were examined in vitro for their antiproliferative activity on MCF-7, NCI-ADR, NCI-460, UACC-62, 786-0, OVCAR-03, PCO-3 and HT-29 human cancer cell lines. Among the assayed fractions, the ethyl acetate fraction showed to be cytotoxic against 786-0, UACC-62, OVCAR-03 and NCI-ADR cell lines with IC50 values of 12 μg/mL, 42 μg/mL, 53 μg/mL and 51 μg/mL, respectively. Through fractionation and isolation procedures compound (1) was obtained from the EtOAc fraction and its structure was elucidated by spectral techniques.pt_BR
dc.identifier.citationROMERO, Adriano Lopes et al. Atividade antiproliferativa de Sloanea garckeana K. Schum. Química Nova, São Paulo, v. 31, n. 6, p. 1359-1361, 2008.pt_BR
dc.identifier.issn0100-4042
dc.identifier.issne- 1678-7064
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/15306
dc.language.isoporpt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentInstituto de Química - IQ (RG)pt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectSloanea garkeanapt_BR
dc.subjectElaeocarpaceaept_BR
dc.subjectO-methyl ellagic acid-4’-O-α-L-rhamnosidept_BR
dc.titleAtividade antiproliferativa de Sloanea garckeana K. Schumpt_BR
dc.title.alternativeAntiproliferative activity of Sloanea garckeana K. Schumpt_BR
dc.typeArtigopt_BR

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