Decline of hepatitis C infection in hemodialysis patients in Central Brazil: a ten years of surveillance

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dc.creatorCarneiro, Megmar Aparecida dos Santos
dc.creatorTeles, Sheila Araujo
dc.creatorMatos, Márcia Alves Dias de
dc.creatorSouto, Renata Carneiro Ferreira
dc.creatorNaghettine, Alessandra Vitorino
dc.creatorSilva, Simonne Almeida e
dc.creatorLampe, Elisabeth
dc.creatorYoshida, Clara Fumiko Tachibana
dc.creatorMartins, Regina Maria Bringel
dc.date.accessioned2022-07-08T12:46:23Z
dc.date.available2022-07-08T12:46:23Z
dc.date.issued2005-07
dc.description.abstractHepatitis C virus (HCV) has been a significant problem for hemodialysis patients. However this infection has declined in regions where the screening for anti-HCV in blood banks and hemodialysis-specific infection control measures were adopted. In Brazil, these measures were implemented in 1993 and 1996, respectively. In addition, all studied units have implemented isolation of anti-HCV positive patients since 2000. In order to evaluate the impact of these policies in the HCV infection prevalence, accumulated incidence, and risk factors in hemodialysis population of Goiânia City, Central Brazil, all patients were interviewed and serum samples tested for HCV antibodies in 1993, 1996, 1999, and 2002. In the first six years (1993-1999), anti-HCV prevalence increased from 28.2 to 37.2%, however a strong decrease in positivity was detected between 1999 and 2002 (37.8 vs 16.5%) when the measures were fully implemented. Also, a decrease of the anti-HCV accumulated incidence in cohorts of susceptible individuals during 1993-2002 (71%), 1996-2002 (34.2%), and 1999-2002 (11.7%) was found. Analysis of risk factors showed that length of time on hemodialysis, blood transfusion before screening for anti-HCV and treatment in multiple units were statistically associated with anti-HCV (p < 0.05). Our study showed a significant decline of hepatitis C infection in hemodialysis patients of Central Brazil, ratifying the importance of public health strategies for control and prevention of hepatitis C in the hemodialysis units.pt_BR
dc.identifier.citationCARNEIRO, Megmar A. S. et al. Decline of hepatitis C infection in hemodilayis patients in Central Brazil: a 10-year of surveillance. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 100, n. 4, p. 345-349, July 2005.pt_BR
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/20936
dc.language.isoengpt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFaculdade de Medicina - FM (RG)pt_BR
dc.rightsAcesso Abertopt_BR
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectHepatitis Cpt_BR
dc.subjectCentral Brazilpt_BR
dc.subjectHemodialysispt_BR
dc.subjectPrevalencept_BR
dc.subjectIncidencept_BR
dc.subjectRisk factorspt_BR
dc.titleDecline of hepatitis C infection in hemodialysis patients in Central Brazil: a ten years of surveillancept_BR
dc.typeArtigopt_BR

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