Dementia and behavioral disorders in Progressive Multifocal Leukoencephalopathy (PML) - case report

Abstract

Psychiatric disturbances in Progressive Multifocal Leukoencephalo pathy (PML) are rarely adressed and its study can offer insights into the neurobiology of psychosis. The authors report a case of male pa tient, 42 years old, HIV positive, with PML and psychotic symptoms. The present case shows the need for regular neurological and neu ropsychological evaluations of HIV positive patients and the impor tance of studying diseases that cause lesions in the white matter, such as PML, to elucidate the neurobiology of psychosis.