Tandem chalcone-sulfonamide hybridization, cyclization and further Claisen–Schmidt condensation: tuning molecular diversity through reaction time and order and catalyst

Página do item simplificado
dc.creatorCastro, Mirian Rita Carrilho de
dc.creatorNaves, Raquel Ferreira
dc.creatorValeze, Aline Bernardes
dc.creatorSilva, Cameron Capeletti da
dc.creatorNoda Pérez, Caridad
dc.creatorMoura, Andrea Felinto
dc.creatorMoraes Filho, Manoel Odorico de
dc.creatorMartins, Felipe Terra
dc.date.accessioned2023-08-25T15:46:34Z
dc.date.available2023-08-25T15:46:34Z
dc.date.issued2020
dc.description.abstractWe here report the synthesis of novel chalcone-sulfonamide compounds based on the hybridization at 2′ position and nitro substitution at the side chalcone phenyl ring followed by tandem cyclization into quinolinone derivatives and then a further aldol condensation only as a function of the reaction time. Therefore, for the first time, we have controlled the sequential preparation of chalcone-sulfonamide hybrids, quinolinones and then (E)-3-ene-2,3-dihydroquinolinones simply stopping reaction over increasing time periods. Furthermore, a new molecular scaffold based on a chalcone-(bis)sulfonamide hybrid has been gotten through changing the sequence of coupling reactions and catalyst. This study means practical and useful ways of constructing in high yields new biologically active compounds bearing diversified molecular scaffolds.pt_BR
dc.identifier.citationCASTRO, Mirian R. C. de. et al. Tandem chalcone-sulfonamide hybridization, cyclization and further Claisen–Schmidt condensation: tuning molecular diversity through reaction time and order and catalyst. Arabian Journal of Chemistry, Amsterdam, v. 13, p. 1345-1354, 2020. DOI: 10.1016/j.arabjc.2017.11.005. Disponível em: https://www.sciencedirect.com/science/article/pii/S1878535217302137?via%3Dihub. Acesso em: 24 ago. 2023.pt_BR
dc.identifier.doi10.1016/j.arabjc.2017.11.005
dc.identifier.issn1878-5352
dc.identifier.issne- 1878-5379
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/23441
dc.language.isoengpt_BR
dc.publisher.countryHolandapt_BR
dc.publisher.departmentInstituto de Química - IQ (RMG)pt_BR
dc.rightsAcesso Abertopt_BR
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectMolecular hybridizationpt_BR
dc.subjectChalconept_BR
dc.subjectSulfonamidept_BR
dc.subjectQuinolinonept_BR
dc.subjectTandem reactionspt_BR
dc.subjectClaisen–Schmidt condensationpt_BR
dc.titleTandem chalcone-sulfonamide hybridization, cyclization and further Claisen–Schmidt condensation: tuning molecular diversity through reaction time and order and catalystpt_BR
dc.typeArtigopt_BR

Arquivos

Pacote Original
Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
Artigo - Mirian Rita Carrilho de Castro - 2020.pdf
Tamanho:
1.66 MB
Formato:
Adobe Portable Document Format
Descrição:
Baixar
Licença do Pacote
Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Baixar

Coleções

IQ - Artigos publicados em periódicos