HR-MAS NMR for rapid identification of illicit substances in tablets and blotter papers seized by police department
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Data
2016-04-06
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Resumo
Illicit substances found in blotter papers and tablets seized by police are traditionally identified
and characterized from extracts of these materials. However, the procedures involved in extraction
stages can result in artifacts and even contamination of the samples to be analyzed. On the other
hand, high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) is a
technique that requires no pretreatment steps, enabling direct analysis of the material, including
the analysis of new illegal synthetic psychoactive substances. This study presents and discusses
applications of the HR-MAS NMR in the analysis of tablets and blotter papers seized. Additional
analysis in solution of the extracts of these materials was performed to compare the obtained spectral
resolution signals. The results demonstrated that the HR-MAS NMR allowed the rapid identification
of 3,4-methylenedioxy-N-methylcathinone (methylone), 4-methylmethcathinone (mephedrone),
2,5-dimethoxy-4-bromoamphetamine (DOB) and 2-(4-bromo-2,5-dimethoxyphenyl)-N-[(2-
methoxyphenyl)methyl]ethanamine (25B-NBOMe) in samples of tablets and blotter papers seized
in Goiás State, Brazil.
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Designer drugs, Psychoactive substances, ¹H HR-MAS NMR, Fast identification
Citação
SOUZA, Luciano F. et al. HR-MAS NMR for rapid identification of illicit substances in tablets and blotter papers seized by police department. Journal of the Brazilian Chemical Society, Campinas, v. 27, n. 11, p. 2141-2148, 2016. DOI: 10.1016/j.jphotobiol.2016.03.042. Disponível em: https://jbcs.sbq.org.br/default.asp?ed=244. Acesso em: 16 fev. 2024.