Infecções agudas do sistema nervoso central (SNC) e doença meningocócica em Goiás. (1971-1994)

Abstract

This work reports lhe occurrence of 9.888 hospitalized cases in Goiânia, in which 4.027 (40,73%) originated from the Capital and 5.861 (59,27%) from small towns nearby in the State of Goiás. This number represents 56,96% of the notitled cases (17.359). Bacterial infections were 4.149 (41,96%), 3.103 (31,38%) werc menhigucoccal disease and 2.636 (26,66%), the aseptic form. Among the bacterial ones, the etiologic agent was isolated only in 980 (23,62%) as follows: Haemophvlux influenzae, 41 1 (9,91%), Streptococcus pneumoniae, 359 (8,65%), Staphylococcus xp., 151 (3,64%) and Streptococcus sp. 59 (1,42%). Antibiotics administration before hospitalization were investigated in cerebrospinal fluid of 278 patients and detected in 33 (11,87%). Among the aseptic ones, 80 (3,03%) were classifled as tuberculous, according to the clinicai, radiological and epidemiological fíndings. The attempts to identify Mycobacterium tuberculosis in cerebrospinal fluid by microscópica! examination and cultures were unsuccessful. In 37 (1,40%) of the clear cerebrospinal fluids, Cryptococcus neoformans were identified and isolated buí they were not related to AIDS. Neisseria meningitidis were identified and isolated in 2.950 (95,07%) patients by microscopical examination, culture and/or counterimmuneletrophoresis. In 153 (4,93%) patients, meningococcal disease was classified according to the clinicai findings. Hemorrhagic cutaneous injuries with or without vascular shock. 4.438 (44,88%) were under five years old. The death rate was bigger in patients over fifly (28,82%) than in children under five years old (27,12%).