Infecções de transmissão vertical em material abortivo e sangue com ênfase em Toxoplasmose gondii
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Data
2014-01
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Resumo
To analyze the serological, anatomopathological and parasitological results obtained from abortive material
in order to detect infections with the risk of vertical transmission, with emphasis on toxoplasmosis. METHODS: A cross-
sectional cohort study was conducted in order to determine the prevalence of infectoparasitic diseases. A total of 105
women who suffered spontaneous complete or incomplete abortion participated in the study. The women were interviewed,
answered a questionnaire and had their blood and abortive material collected. Immunological tests were carried out
in order to detect toxoplasmosis, Chagas disease, rubeola, cytomegalovirus and syphilis, and anatomopathological
analysis of the ovular remains was performed. RESULTS: 55% of the women studied were 20 to 30 years old. Most
of them (68%) presented a gestational age between the 7 th and 14 th week. 54.3% of the women had complete or
incomplete high school education. Serological analysis showed cytomegalovirus (CMV) as the most common vertically
transmitted infection with 97.1% positivity, followed by rubeola with 95.2%. Toxoplasmosis showed 54.3% positivity,
Chagas disease 1.9% and syphilis 0.95%. Anatomopathological analysis showed inflammation in 63.1% of the
cases and absence of inflammation in 34%. The results of the serological, anatomopathological and parasitological
analysis of the 105 participants showed that 57 women were T. gondii positive. However, none showed positivity in
the polymerase chain reaction (PCR) or in mouse inoculation. CONCLUSIONS: The prevalence of diseases with the
risk of vertical transmission is important in women with spontaneous abortion, indicating the need for more research in
order to investigate the etiology of abortion.
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Infecção/congênito, Toxoplasmose/transmissão, Aborto/etiologia, Transmissão vertical de doença infecciosa, Infection/congenital, Toxoplasmosis/transmission, Infectious disease transmission, vertical, Abortion/etiology
Citação
BARBARESCO, Aline Almeida; COSTA, Tatiane Luiza da; AVELAR, Juliana Boaventura; RODRIGUES, Isolina Maria Xavier; AMARAL, Waldemar Naves do; CASTRO, Ana Maria de. Infecções de transmissão vertical em material abortivo e sangue com ênfase em Toxoplasmose gondii. Revista Brasileira de Ginecologia e Obstetrícia, Rio de Janeiro, v. 36, n. 1, p. 17-22, jan. 2014.