Correlação de presença de linhas B em ultrassonografia pulmonar e elevação de BNP em pacientes com insuficiência cardíaca
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Data
2024-06-28
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Universidade Federal de Goiás
Resumo
Cardiovascular diseases (CVD) are one of the leading causes of death globally, with heart failure (HF) affecting approximately 64 million people, posing a significant public health challenge. Dyspnea is a common symptom of HF. Biomarkers and imaging play a crucial role in disease diagnosis and management. Bedside pulmonary ultrasound (US) assessing B lines is a useful tool for evaluating pulmonary congestion, correlating positively with elevated brain natriuretic peptide (BNP), an important biomarker for HF diagnosis and prognosis. In Brazil, HF is the leading cause of hospital admissions under the Unified Health System (SUS). Early intervention during decompensation episodes is essential to control symptoms, reduce
hospital stay, improve quality of life, and decrease work disability and costs. OBJECTIVE: To evaluate the positive correlation between B-lines in pulmonary US and elevated BNP levels in patients with cardiac-related dyspnea. METHODOLOGY: This study is an integrative literature review aiming to organize and analyze publications on the correlation between B-lines in pulmonary ultrasound and elevated BNP in HF patients. Using the PICO strategy, a search on PUBMED yielded 59 studies, of which 28 were selected by two evaluators using the RAYYAN tool. RESULTS AND DISCUSSION: The International Consensus on Pulmonary US showed high sensitivity in detecting pulmonary congestion, surpassing the diagnostic accuracy of chest radiographs and NT-proBNP. Randomized studies indicated that combining pulmonary US with clinical evaluation significantly improves sensitivity and specificity in HF diagnosis. Integrated US approaches demonstrated superiority in sensitivity and specificity compared to BNP. In emergencies, pulmonary US proved more accurate and easier to implement. In primary care, US was also effective, especially when used alongside BNP. CONCLUSION: US protocols demonstrate high sensitivity and specificity in detecting pulmonary congestion, thereby enhancing HF management.
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Palavras-chave
Insuficiência cardíaca, Ultrassonografia pulmonar, Peptídeo Natriurético Cerebral (BNP), Linha B, Heart failure, Pulmonary ultrasonography, Brain Natriuretic Peptide (BNP), B-line
Citação
MEDEIROS, João Lucas Brasil; OLIVEIRA, João Paulo Borges de. Correlação de presença de linhas B em ultrassonografia pulmonar e elevação de BNP em pacientes com insuficiência cardíaca. 2024. 21 f. Trabalho de Conclusão de Curso (Bacharelado em Medicina) - Faculdade de Medicina, Universidade Federal de Goiás, Goiânia, 2024.