Biocurativos e suas aplicações em medicina regenerativa: uma revisão descritiva

Abstract

Biocuratives are part of an area of research and technology that advances the development of biological materials in order to repair or regenerate tissues, generating healing in chronic and advanced injuries. These materials have excellent properties such as: biocompatibility, low toxicity, biological adaptability, sustainability, potential for customization, among others. The aim of the latest research on biocuratives is to promote effective cellular therapy, with high regenerative power, maintaining tissue function in advanced, chronic injuries or in wounds that do not heal in a timely manner, generating disruption and compromising the lives of patients. There are several targets of interest in the scientific community in clinical treatments, regenerative medicine stands out, since such biological dressings have the power to intervene in hydroelectrolytic losses, avoid bacterial contamination, favor the epithelialization of granulation tissues for grafting, being widely used in burns, chronic ulcers, reconstructive surgeries and others, being highly explored in clinical uses. The latest clinical research has demonstrated favorable results, along with histological presentations, tensiometric and histochemical properties, in the different aspects related to such materials. The objective of this review was to present the main aspects that biocuratives present regarding their use in tissue engineering, cell therapy and tissue regeneration. From this review, it was observed that future studies should emphasize the production of biological materials together with clinical trials to promote wound healing, with success.