Serodiagnosis of chronic and acute Chagas´disease with Trypanosoma cruzi recombinant proteins: results of a collaborative study in six Latin American countries
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2004-01
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Resumo
An enzyme-linked immunosorbent assay to diagnose Chagas’ disease by a serological test was performed
with Trypanosoma cruzi recombinant antigens (JL8, MAP, and TcPo). High sensitivity (99.4%) and specificity
(99.3%) were obtained when JL8 was combined with MAP (JM) and tested with 150 serum samples from
chagasic and 142 nonchagasic individuals. Moreover, JM also diagnosed 84.2% of patients in the acute phase
of T. cruzi infection
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Collaborative study, Trypanosoma cruzi, Chagas disease, Serodiagnosis
Citação
UMEZAWA, Eufrosina S.; LUQUETTI, Alejandro O.; LEVITUS, Gabriela; PONCE, Carlos; PONCE, Elisa; HENRIQUEZ, Diana; REVOLLO, Susana; ESPINOZA, Bertha; SOUSA, Octavio; KHAN, Baldip; SILVEIRA, José Franco da. Serodiagnosis of chronic and acute Chagas´disease with Trypanosoma cruzi recombinant proteins: results of a collaborative study in six Latin American countries. Journal of Clinical Microbiology, Washington, v. 42, n. 1, p. 449-452, Jan. 2004.