The feasibility of an experimental model of donors after cardiac death in remote ischemic preconditioning studies for renal transplantation in porcine

dc.creatorCamarço, João Paulo Figueiredo
dc.creatorMorais, Lucio Kenny
dc.creatorMoreno, Juan Carlos Duque
dc.creatorRassi, Matheus Castrillon
dc.creatorCamarço, Mylena Naves de Castro Rocha
dc.creatorGuimarães, Pedro Figueiredo
dc.creatorQuireze Júnior, Claudemiro
dc.date.accessioned2017-11-29T11:07:36Z
dc.date.available2017-11-29T11:07:36Z
dc.date.issued2014
dc.description.resumoTo evaluate the feasibility of an experimental model of donors after cardiac death in remote ischemic preconditioning studies. METHODS: Twelve Landrace pigs were used as organ donors. They underwent cardiac arrest by coronary en block suture and interruption of ventilatory support. Haemodynamic data regarding the donor surgical protocol were evaluated. Studies variables included mean heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure, central venous pressure and oxygen saturation and the time to death. RESULTS: Haemodynamic parameter indicated that the circulatory failure occurred after nine minutes of en block coronary suture and respiratory support interruption. The circulatory collapse occurred evenly across all groups. The heart rate and central venous pressure were statistically different between groups (p=0.023 and p=0.04), respectively. The remote preconditioning resulted in delayed time of death. CONCLUSIONS: The model is feasible, and was easily reproduced. The ischemic remote preconditioning tends to a slight increase in circulatory failure time.pt_BR
dc.identifier.citationCAMARÇO, João Paulo Figueiredo; MORAIS, Lucio Kenny; MORENO, Juan Duque; RASSI, Matheus Castrillon; CAMARÇO, Mylena Naves de Castro Rocha; GUIMARÃES, Pedro Figueiredo; QUIREZE JÚNIOR, Claudemiro. The feasibility of an experimental model of donors after cardiac death in remote ischemic preconditioning studies for renal transplantation in porcine. Acta Cirúrgica Brasileira, São Paulo, v. 29, n. 2, p. 82-86, 2014.pt_BR
dc.identifier.doi10.1590/S0102-86502014000200002
dc.identifier.issne- 1678-2674
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/13034
dc.language.isoengpt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentEscola de Veterinária e Zootecnia - EVZ (RG)pt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectIschemic preconditioningpt_BR
dc.subjectKidney transplantationpt_BR
dc.subjectOrgan preservationpt_BR
dc.subjectSwinept_BR
dc.titleThe feasibility of an experimental model of donors after cardiac death in remote ischemic preconditioning studies for renal transplantation in porcinept_BR
dc.typeArtigopt_BR

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