Anxiety and depression in patients with primary glomerulopathies

Abstract

Objective: The objective of this study was to evaluate the anxiety and depression domains of patients with primary glomerulopathies from the patients’ perspective via patient-reported outcome measurements and to identify the factors associated with worse scores. Materials and methods: This was a cross-sectional study involving 46 patients in which a patient-reported outcome measurement instrument was applied to evaluate the domains of anxiety and depression in patients with primary glomerulopathies. Exploratory univariate statistical analyses were performed, followed by multiple linear regression analyses. Results: 46 patients participated in the study. The mean age was 38.5 ± 16.4 years. The anxiety T score was 58.6%, and the depression T score was 54.7%. Female patients had worse anxiety scores (p = 0.044) and depression scores (p = 0.040). Patients under 60 years of age had worse anxiety scores (p = 0.041). A lower educational level was related to a worse depression score (p = 0.010). The concomitant presence of diabetes mellitus and a diagnosis time ≥ 9 months were associated with worse anxiety scores (p = 0.015 and p = 0.014) and depression (p = 0.012 and p = 0.007). Conclusion: Patients with primary glomerulopathies have more anxiety and depression, and the variables associated with worse scores are female sex, age under 60 years, lower educational level, time since diagnosis, and diabetes mellitus.