In vitro characterization of virulence factors among species of the Candida parapsilosis complex
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2020
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Introduction: Candida parapsilosis complex species differ from each other with regard to their prevalence and virulence. Methods:
The hydrolytic enzyme activity, biofilm production, and adhesion to epithelial cells were analyzed in 87 C. parapsilosis complex
strains. Results: Among the studied isolates, 97.7%, 63.2%, and 82.8% exhibited very strong proteinase, esterase, and hemolysin
activity, respectively. All the C. parapsilosis complex isolates produced biofilms and presented an average adherence of 96.0 yeasts/100
epithelial cells. Conclusions: Our results show that Candida parapsilosis complex isolates showed different levels of enzyme activity,
biofilm production, and adhesion to epithelial cells.
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Candida parapsilosis, Virulence factors, Biofilms, Cell adhesion, Hydrolytic enzymes
Citação
ATAIDES, Fábio Silvestre et al. In vitro characterization of virulence factors among species of the Candida parapsilosis complex. Revista da Sociedade Brasileira de Medicina Tropical, Rio de Janeiro, v. 53, e20190336, 2020. DOI: 10.1590/0037-8682-0336-2019. Disponível em: https://www.scielo.br/j/rsbmt/a/JhqWRnc36k54xP8LtkWQzdF/?lang=en. Acesso em: 5 jun. 2025.