In vitro characterization of virulence factors among species of the Candida parapsilosis complex

dc.creatorAtaídes, Fábio Silvestre
dc.creatorCosta, Carolina Rodrigues
dc.creatorSantos, Andressa Santana
dc.creatorFreitas, Vivianny Aparecida Queiroz
dc.creatorSilva, Thaísa Cristina
dc.creatorZara, Ana Laura de Sene Amâncio
dc.creatorJesuino, Rosalia Santos Amorim
dc.creatorSilva, Maria do Rosário Rodrigues
dc.date.accessioned2025-06-06T11:45:36Z
dc.date.available2025-06-06T11:45:36Z
dc.date.issued2020
dc.description.abstractIntroduction: Candida parapsilosis complex species differ from each other with regard to their prevalence and virulence. Methods: The hydrolytic enzyme activity, biofilm production, and adhesion to epithelial cells were analyzed in 87 C. parapsilosis complex strains. Results: Among the studied isolates, 97.7%, 63.2%, and 82.8% exhibited very strong proteinase, esterase, and hemolysin activity, respectively. All the C. parapsilosis complex isolates produced biofilms and presented an average adherence of 96.0 yeasts/100 epithelial cells. Conclusions: Our results show that Candida parapsilosis complex isolates showed different levels of enzyme activity, biofilm production, and adhesion to epithelial cells.
dc.identifier.citationATAIDES, Fábio Silvestre et al. In vitro characterization of virulence factors among species of the Candida parapsilosis complex. Revista da Sociedade Brasileira de Medicina Tropical, Rio de Janeiro, v. 53, e20190336, 2020. DOI: 10.1590/0037-8682-0336-2019. Disponível em: https://www.scielo.br/j/rsbmt/a/JhqWRnc36k54xP8LtkWQzdF/?lang=en. Acesso em: 5 jun. 2025.
dc.identifier.doi10.1590/0037-8682-0336-2019
dc.identifier.issn0037-8682
dc.identifier.issne- 1678-9849
dc.identifier.urihttp://repositorio.bc.ufg.br//handle/ri/27716
dc.language.isoeng
dc.publisher.countryBrasil
dc.publisher.departmentInstituto de Patologia Tropical e Saúde Pública - IPTSP (RMG)
dc.rightsAcesso Aberto
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectCandida parapsilosis
dc.subjectVirulence factors
dc.subjectBiofilms
dc.subjectCell adhesion
dc.subjectHydrolytic enzymes
dc.titleIn vitro characterization of virulence factors among species of the Candida parapsilosis complex
dc.typeArtigo

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