Hepatite infecciosa canina em um cão geriátrico naturalmente infectado

Página do item simplificado
dc.creatorRossato, Cristina Krauspenhar
dc.creatorMartins, Danieli Brolo
dc.date.accessioned2017-09-12T13:37:31Z
dc.date.available2017-09-12T13:37:31Z
dc.date.issued2015-09
dc.description.abstractInfectious canine hepatitis (ICH) is a systemic viral disease of dogs. It affects mainly unvaccinated dogs under the age of six months. Although clinical signs of ICH are not specific, the necropsy findings are sufficient to allow a presumptive diagnosis associated with epidemiology and clinical signs. Clinician should suspect the disease when two years-old dogs or younger present acute death with abdominal pain, neurological disorders and signs of bleeding. The objective of this study is to report an unusual case of ICH, describing the clinical and pathological findings in a geriatric dog with the disease. Case: A female Basset Hound dog, 9 year-old, was presented with intense vomiting and diarrhea in the last day. The animal was not vaccinated there was two years. The blood count revealed moderate leukocytosis by neutrophils and deviation to the left and to the right, and monocytosis, besides lymphopenia and eosinopenia. It was also possible to observe hyperproteinemia and plasma intensely jaundiced. The biochemical examination showed alterations in liver and kidney parameters. After three days of hospitalization, the patient was euthanized and submitted for necropsy. Macroscopic findings consisted of increased dark red liver, and fibrin strands in the capsular surface. There was a bloody fluid in the small intestine and stomach. Serous small intestine showed granular appearance. Kidneys were dark red aspect. There was ecchymosis in the lung. Histopathological analysis of the liver showed severe hemorrhage with multifocal hepatocellular necrosis randomized and intense mixed inflammatory infiltrate composed of lymphocytes, plasma cells and macrophages, mainly in the periportal region with presence of intranuclear inclusions in hepatocytes, which were amphophilic (characteristic of adenovirus); some of them met all the core, but most showed clear halo between inclusion and the limit of the nuclear membrane. Kidneys had rare amphophilic intranuclear inclusion bodies in renal glomerulus. Discussion: Most authors recognize ICH mainly affecting young animals (up to two years). Factors related to vaccination as poor preservation of the product, mode of application and improper intervals between applications; or attached to the patient, such as stress and concomitant diseases, will contribute to the occurrence of the infection. The reported dog was delayed vaccination program there was two years ago, which may also have interfered with immune status. The dog in this case had clinical suspicion of liver disease, and there was not initial suspicion of ICH, which can be related to the difficulty of making a clinical diagnosis of this disease, since the signs are nonspecific. This fact reinforces the importance of the definitive diagnosis of ICH that be confirmed by histopathology and/or supplementary diagnosis. The blood count of the patient showed an inflammatory WBC count with possible influence of stress. Furthermore, hyperproteinemia was related to the dehydration caused by vomiting and diarrhea and/or antigenic stimulation. In this patient, macroscopic findings were suggestive of HIC, while histological analysis confirmed our suspect. The diagnosis of the disease, in this case, was possible by the histopathological analysis that allowed the identification of intranuclear inclusion bodies in the liver and kidneys, which are characteristic of the canine adenovirus type 1.pt_BR
dc.identifier.citationROSSATO, Cristina Krauspenhar; MARTINS, Danieli Brolo. Hepatite infecciosa canina em um cão geriátrico naturalmente infectado. Acta Scientiae Veterinariae, Porto Alegre, v. 43, p. 1-4, set. 2015.pt_BR
dc.identifier.issne- 1679-9216
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/12383
dc.language.isoporpt_BR
dc.publisherUniversidade Federal do Rio Grande do Sulpt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentEscola de Veterinária e Zootecnia - EVZ (RG)pt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectCanine adenovirus type 1pt_BR
dc.subjectInclusion bodiespt_BR
dc.subjectLiverpt_BR
dc.subjectKidneypt_BR
dc.subjectAdenovírus canino tipo 1pt_BR
dc.subjectCorpúsculos de inclusãopt_BR
dc.subjectFígadopt_BR
dc.subjectRimpt_BR
dc.titleHepatite infecciosa canina em um cão geriátrico naturalmente infectadopt_BR
dc.title.alternativeInfectious canine hepatitis in an aged dog naturally infectedpt_BR
dc.typeArtigopt_BR

Arquivos

Pacote Original
Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
Artigo - Cristina Krauspenhar Rossato - 2015.pdf
Tamanho:
781.71 KB
Formato:
Adobe Portable Document Format
Baixar
Licença do Pacote
Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Baixar

Coleções

EVZ - Artigos publicados em periódicos