Anti-inflammatory, antinociceptive, and sedating effects of lafoensia pacari aqueous extract

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dc.creatorMatos, Lécia Garcia de
dc.creatorSantos, Lucio da Ressurreição
dc.creatorFerreira, Reginaldo Nassar
dc.creatorPontes, Itamar dos Santos
dc.creatorPaula, José Realino de
dc.creatorCosta, Elson Alves
dc.date.accessioned2021-01-26T15:45:26Z
dc.date.available2021-01-26T15:45:26Z
dc.date.issued2008
dc.description.abstractThe acetic acid–induced abdominal writhing, the tail flick, and the croton oil–induced mouse ear edema tests were used to study the anti-inflammatory effects of the aqueous extract from Lafoensia pacari A. St.-Hil. (Lythraceae) stem bark. Pentobarbital-induced sleeping timewas used to study the central nervous system depressant effect of the extract. The aqueous extract caused a dose-dependent inhibition of acetic acid–induced abdominal writhing and ear edema formation and produced a significant (p < 0.05) dose-related increase in the duration of sleep. The results suggest that Lafoensia pacari stem bark contains compounds with antiinflammatory, analgesic, and central depressant actions.pt_BR
dc.identifier.citation1-MATOS, Lecia G. de et al. Anti-inflammatory, antinociceptive, and sedating effects of lafoensia pacari aqueous extract. Pharmaceutical Biology, London, v. 46, n. 5, p. 341-346, 2008.pt_BR
dc.identifier.doi10.1080/13880200801887799
dc.identifier.issn1388-0209
dc.identifier.issne- 1744-5116
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/19308
dc.language.isoengpt_BR
dc.publisher.countryGra-bretanhapt_BR
dc.publisher.departmentInstituto de Ciências Biológicas - ICB (RG)pt_BR
dc.rightsAcesso Abertopt_BR
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectAnalgesic activitypt_BR
dc.subjectAnti-inflammatory effectpt_BR
dc.subjectCentral depressant actionspt_BR
dc.subjectLafoensia pacaript_BR
dc.subjectEar edemapt_BR
dc.subjectLythraceaept_BR
dc.titleAnti-inflammatory, antinociceptive, and sedating effects of lafoensia pacari aqueous extractpt_BR
dc.typeArtigopt_BR

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