Equisetum arvense: scientific evidences for clinical use

Resumo

Equisetum arvense L. (horsetail) is a medicinal plant that is native to Europe and also commonly found in the Americas, Northern Africa and Asia. It has been traditionally indicated as a mild diuretic, antiedematous, anti-inflammatory and remineralizing treatment. The aim of this study was to review the literature concerning horsetail to provide support to phytotherapy researchers and policymakers interested in data on this medicinal plant. The literature review was conducted using the PubMed, LILACS, SciELO, Virtual Health Library (VHL), Cochrane and Scopus databases, from July 2011 to July 2012, using the uniterm "Equisetum arvense". The study included 58 articles involving pharmacognostic, pharmacological, pharmacokinetic, in vivo toxicological and clinical studies focusing on E. arvense as an herbal drug or an extract. The results of preclinical pharmacological studies demonstrate several important in vitro and in vivo biological activities, including antioxidant, sedative, antimicrobial, antiplatelet, cytotoxic, vasorelaxant, hepatoprotective, antidiabetic, analgesic, anti-inflammatory, wound-healing, remineralizing, antilithiasic and diuretic activities. No clinical studies supporting the use of horsetail as a diuretic or studies on the mechanism of action of horsetail extracts were identified. Horsetail has been classified as a traditional- and popular-use drug whose uses must be regulated and whose research needs to be encouraged.

Descrição

Palavras-chave

Phytotherapy, Medicinal plants, Equisetum arvense, Traditional medicine, Ethnopharmacology

Citação

CARNEIRO, D. M.; TRESVENZOL, L. M. F.; JARDIM P. C. B. V.; CUNHA, L. C. Equisetum arvense: scientific evidences for clinical use. International Journal of Biology, Pharmacy and Allied Sciences, v. 2, n. 8, p. 1579-1596, Aug. 2013.