Dereplication by HPLC-ESI-MS and antioxidant activity of phenolic compounds from Banisteriopsis laevifolia (Malpighiaceae)

Página do item simplificado
dc.creatorAlexandre, Gerso Pereira
dc.creatorSimão, Jorge Luiz Souza
dc.creatorTavares, Maria Olivia Amaral
dc.creatorZuffo, Izabella Mariana de Souza
dc.creatorPrado, Stéphanie Vilela
dc.creatorPaiva, Joseilson Alves de
dc.creatorMustapha, Abubakar
dc.creatorOliveira, Anselmo Elcana de
dc.creatorKato, Lucilia
dc.creatorSeverino, Vanessa Gisele Pasqualotto
dc.date.accessioned2023-06-15T11:50:01Z
dc.date.available2023-06-15T11:50:01Z
dc.date.issued2022
dc.description.abstractThe genus Banisteriopsis (Malpighiaceae) comprises 77 genera and 1,300 species. Despite efforts to provide detailed information about the chemical wealth of B. laevifolia, this article provides the identification and characterization of compounds from the ethanolic extracts of the leaves and flowers using advanced methodologies which include high-performance liquid chromatography coupled to tandem mass spectrometry, which contribute to the knowledge about compounds present in the genus Banisteriopsis. The dereplication aided by Global Natural Products Social Molecular Networking afforded the identification of seven compounds reported for this species for the first time. A mixture of two known flavonoids and a diterpenoid, 18-hydroxy-ent-halima-1(10),13- (E)-dien-15-oic acid, were isolated by conventional separation methods. The elevated 2,2-diphenyl-1-picrylhydrazyl radical scavenging activity observed in some samples was attributed to either the type of extract, the presence of 3,4,5-trihydroxybenzoic acid, or the influence of the substitution pattern and the synergistic effect of the compounds present. Principal Component Analysis was applied to correlate mass spectrometry data with the antioxidant activity of the samples. The high diversity of metabolites found in this study and those which have been reported for Banisteriopsis strongly recommends further investigation into the chemical and biological properties of these species.pt_BR
dc.identifier.citationALEXANDRE, Gerso P. et al. Dereplication by HPLC-ESI-MS and antioxidant activity of phenolic compounds from Banisteriopsis laevifolia (Malpighiaceae). Anais da Academia Brasileira de Ciências, Rio de Janeiro, v. 94, n. 1, e20201844, 2022. DOI: 10.1590/0001-3765202220201844. Disponível em: https://www.scielo.br/j/aabc/a/rs8frBv8bFhNSS6FLZHcMvR/?lang=en. Acesso em: 14 jun. 2023.pt_BR
dc.identifier.doihttps://doi.org/10.1590/0001-3765202220201844
dc.identifier.issn0001-3765
dc.identifier.issne- 1678-2690
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/22734
dc.language.isoengpt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentInstituto de Química - IQ (RMG)pt_BR
dc.rightsAcesso Abertopt_BR
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectBanisteriopsis laevifoliapt_BR
dc.subjectPhenolic compoundspt_BR
dc.subjectAntioxidant activitypt_BR
dc.subjectMolecular networkingpt_BR
dc.subjectDereplicationpt_BR
dc.titleDereplication by HPLC-ESI-MS and antioxidant activity of phenolic compounds from Banisteriopsis laevifolia (Malpighiaceae)pt_BR
dc.typeArtigopt_BR

Arquivos

Pacote Original
Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
Artigo - Gerso Pereira Alexandre - 2022.pdf
Tamanho:
996.97 KB
Formato:
Adobe Portable Document Format
Descrição:
Baixar
Licença do Pacote
Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Baixar

Coleções

IQ - Artigos publicados em periódicos