Acute immune response to mycobacterium massiliense in C57BL/6 and BALB/c mice

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dc.creatorSousa, Eduardo Martins de
dc.creatorBortoli, Fernando Bonfim de
dc.creatorAmaral, Eduardo Pinheiro
dc.creatorBatista, Aline Carvalho
dc.creatorKipnis, Thereza Liberman
dc.creatorCardoso, Alessandra Marques
dc.creatorKipnis, André
dc.creatorJunqueira-Kipnis, Ana Paula
dc.date.accessioned2018-10-29T11:15:38Z
dc.date.available2018-10-29T11:15:38Z
dc.date.issued2010-04
dc.description.abstractMycobacterium massiliense is an environmental opportunistic pathogen that has been associated with soft tissue infection after minor surgery. We studied the acute immune response of C57BL/6 and BALB/c mice infected intravenously with 10 6 CFU of an M. massiliense strain isolated from a nosocomial infection in Brazil. The results presented here show that M. massiliense is virulent and pathogenic to both C57BL/6 and BALB/c mice, inducing a granulomatous inflammatory reaction that involves the activation of macrophages, dendritic cells, and natural killer cells induced by gamma interferon and interleukin-17 (IL-17) in C57BL/6 mice and by IL-12 in BALB/c mice.pt_BR
dc.identifier.citationSOUSA, Eduardo Martins de et al. Acute Immune response to mycobacterium massiliense in C57BL/6 and BALB/c mice. Infection and Immunity, Washington, v. 78, n. 4, p. 1571-1581, Abr. 2010.pt_BR
dc.identifier.doi10.1128/IAI.00731-09
dc.identifier.issn0019-9567
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/16276
dc.language.isoengpt_BR
dc.publisher.countryEstados unidospt_BR
dc.publisher.departmentFaculdade de Odontologia - FO (RG)pt_BR
dc.rightsAcesso Abertopt_BR
dc.titleAcute immune response to mycobacterium massiliense in C57BL/6 and BALB/c micept_BR
dc.typeArtigopt_BR

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