Surveillance of Trypanosoma cruzi transmission by serological screening schoolchildren

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dc.creatorAndrade, Ana Lúcia Sampaio Sgambatti de
dc.creatorZicker, Fabio
dc.creatorOstermayer, Alejandro Luquetti
dc.creatorOliveira, R. M.
dc.creatorSilva, Simonne Almeida e
dc.creatorSouza, José Maria Pacheco de
dc.creatorMartelli, Celina Maria Turchi
dc.date.accessioned2018-04-27T15:53:53Z
dc.date.available2018-04-27T15:53:53Z
dc.date.issued1992
dc.description.abstractThe seroprevalence of Trypanosoma cruzi infection among children is a sensitive indicator for assessing the effectiveness of programmes for control of Chagas disease. In this study we report the result of a cross-sectional serological survey carried out among schoolchildren living in a poor rural area in central Brazil. Eluates of blood collected on filter-paper were tested for anti-T. cruzi antibodies using immunofluorescence, haemagglutination, and enzyme-linked immunosorbent assays. The overall seroprevalence of T. cruzi infection was 7.9%, which compared with the findings of the national survey carried out in 1975-80 indicates that a twofold-to-threefold reduction in prevalence has occurred over the last 10 years. This is consistent with a reduction of transmission in the area, probably related to vector control efforts. Based on our results, the incidence of new cases was estimated to be 44 per annum in the study region. In rural areas with a scattered population, surveillance of T. cruzi transmission by serological screening of children at school entry is more practical and economical than entomological evaluation for assessing both the risk of transmission in the community and the efficacy of vector control measures. A sample size of around 1000 schoolchildren is sufficient to detect prevalences as low as 2%, and such an approach would be practical and applicable to most areas where Chagas disease is endemic.pt_BR
dc.identifier.citationANDRADE, A. L. S. S.; ZICKER, F.; LUQUETTI, A. O.; OLIVEIRA, R. M.; SILVA, S. A.; SOUSA, J. M. P.; MARTELLI, C. M. T. Surveillance of Trypanosoma cruzi transmission by serological screening schoolchildren. Bulletin of the World Health Organization, Washington, v. 70, n. 5, p. 625-629, 1992.pt_BR
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/14729
dc.language.isoengpt_BR
dc.publisher.countryEstados unidospt_BR
dc.publisher.departmentInstituto de Patologia Tropical e Saúde Pública - IPTSP (RG)pt_BR
dc.rightsAcesso Abertopt_BR
dc.titleSurveillance of Trypanosoma cruzi transmission by serological screening schoolchildrenpt_BR
dc.typeArtigopt_BR

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