Doença de inclusão citomegálica - relato de caso

Abstract

The cytomegalic inclusion disease (cytomegalovirus) is the most common viral congenital infection among humans. It is defined as the association between growth restriction, microcephaly, jaundice, hepatosplenomegaly, anemia and thrombocytopenia. Caused by human cytomegalovirus (HCMV), a DNA virus of the Herpesviridae family, it has the human being as a single host. Approximately, 1% of all newborns are infected in the world, being the leading infectious cause that leads to neurological disorders in nature. Its importance increased due to the fact that it can be transmitted by the mother (vertical transmission) in both the acute and the reinfection of the pregnant woman, being asymptomatic or oligosymptomatic in most cases. Because it is a matter of relevance to public health, we report a case of cytomegalovirus infection in that the low titers of IgG associated with morphological changes in fetal ultrasound have led to clinical suspicion. We also emphasize the importance of invasive procedures in the practice of fetal medicine. They were vital in the outcome of this case.