Terapêutica e profilaxia da malária. Revisão
Carregando...
Data
1994-05
Autores
Título da Revista
ISSN da Revista
Título de Volume
Editor
Ruy de Souza Lino Junior
Resumo
There is still no immediate prospect of substantial improvement on control and
possibility of erradication of malária. The old strategy to reduce malária transmission
by vector control hás failed, and nowadays the hope is towards the vaccine. However,
the vaccine is not available yet, só that treatment and preventive measures are the only
accessible tools up to now. In this review the main approach will be on antimalarial
falciparum drugs. The drug choice to Plasmodium ovale, P. malariae and P. vivax lasts
to be the chloroquine. Thus, to P. falciparum the drug choice depends on the sensitivity
of the strains in that region or country. There is an increased resistance to novel drugs
such as mefloquine and halofantrine, but the arthemisin is a great hope to the future.
Nowadays, the best drug for treating malária falciparum in Brazil is quinine plus
tetracicline. Exchange transfusion is a controvérsia! additional measure used i.e., in
cerebral malária and when eritrocytes parasited are grater than 10%. Pregnant woniun
should receive quinino, because there is no real evidence it may cause damage. Thus,
lhere is a great need for new drugs with no compromised efficacy by drug resistance.
Such drugs must to be used with caution and care in order minimize the risk of
emerging resistance.
Descrição
Palavras-chave
Malária, Plasmodium falciparum, Plasmodium malarie, Plasmodium vivax, Resistência a drogas, Profilaxia, Terapêutica, Drugs resistence, Prophylaxis, Treatment
Citação
ANDRADE, João Guimarães de. Terapêutica e profilaxia da malária. Revisão. Revista de Patologia Tropical, Goiânia, v. 23, n. 2, p. 181-190, jul./dez. 1994. Disponível em: <https://www.revistas.ufg.br/iptsp/article/view/20021/11593>.