Hepatitis B virus infection among oncohematologic disease patients in central Brazil: prevalence, risk factors and immunization

Página do item simplificado
dc.creatorPessoni, Grécia Carolina
dc.creatorMarinho, Tassia Augusto
dc.creatorCarneiro, Megmar Aparecida dos Santos
dc.creatorMartins, Regina Maria Bringel
dc.creatorSoares, Caroline Cordeiro
dc.creatorSilva, Leandro Nascimento da
dc.creatorMatos, Márcia Alves Dias de
dc.creatorArantes, Adriano de Moraes
dc.creatorTeles, Juliana Araujo
dc.creatorSantos, Nathalia Carneiro
dc.creatorTeles, Sheila Araújo
dc.date.accessioned2025-03-19T14:17:25Z
dc.date.available2025-03-19T14:17:25Z
dc.date.issued2019
dc.description.abstractIntroduction: Carriers of oncohematological diseases are at high risk for hepatitis B virus (HBV) infection. Objective and method: To investigate the epidemiology of HBV infection in Goiânia, Central Brazil, 322 individuals with oncohematological diseases (leukemias, Hodgkin lymphoma and non-Hodgkin lymphoma) were interviewed and blood samples were collected for the detection of serological markers of HBV-DNA by polymerase chain reaction (PCR). Medical records of participants were also reviewed. Results: Non-Hodgkin’s lymphomas (n = 99) and chronic myeloid leukemia (n = 108) were the most frequent oncohematological diseases. The overall prevalence of HBV was 13.97% (45/322). Of the total participants, 8.69% (28/322) presented isolated positivity for anti-HBs, suggesting low vaccine coverage. HBV-DNA was detected in 25% (1/4) of HBsAg positive sam ples and in 25% (3/12) of anti-HBc isolated, suggesting HBV occultinfection. All samples were identified as subgenotype A1. Entries in patient records and the findings of this investigation suggest anti-HBc seroconversion during oncologic treatment. Age 50 years or over and use of a central catheter during therapy were associated with HBV exposure.
dc.identifier.citationPESSONI, Grécia C. et al. Hepatitis B virus infection among oncohematologic disease patients in central Brazil: prevalence, risk factors and immunization. Hematology, Transfusion and Cell Therapy, Rio de Janeiro, v. 41, n. 3, p. 199-204, 2019. DOI: 10.1016/j.htct.2018.11.008. Disponível em: https://www.sciencedirect.com/science/article/pii/S253113791930032X?via%3Dihub. Acesso em: 7 fev. 2025.
dc.identifier.doi10.1016/j.htct.2018.11.008
dc.identifier.issne- 2531-1387
dc.identifier.issn2531-1379
dc.identifier.urihttp://repositorio.bc.ufg.br//handle/ri/27037
dc.language.isoeng
dc.publisher.countryBrasil
dc.publisher.departmentInstituto de Patologia Tropical e Saúde Pública - IPTSP (RMG)
dc.rightsAcesso Aberto
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectEpidemiology
dc.subjectLeukemia
dc.subjectLymphoma
dc.subjectHepatitis B
dc.subjectOncology
dc.titleHepatitis B virus infection among oncohematologic disease patients in central Brazil: prevalence, risk factors and immunization
dc.typeArtigo

Arquivos

Pacote Original
Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
Artigo - Grécia Carolina Pessoni - 2019.pdf
Tamanho:
611.36 KB
Formato:
Adobe Portable Document Format
Baixar
Licença do Pacote
Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Baixar

Coleções

IPTSP - Artigos publicados em periódicos