Mass screening for Trypanosoma cruzi infections using the immunofluorescence, ELISA and haemagglutination tests on serum samples and on blood eluates from filter-paper
| dc.creator | Zicker, Fabio | |
| dc.creator | Smith, Peter George | |
| dc.creator | Ostermayer, Alejandro Luquetti | |
| dc.creator | Oliveira, O. S. | |
| dc.date.accessioned | 2018-05-11T12:35:21Z | |
| dc.date.available | 2018-05-11T12:35:21Z | |
| dc.date.issued | 1990 | |
| dc.description.abstract | Methods used to diagnose Trypanosoma cruzi infection differ in their ability to discriminate between sera from infected and uninfected individuals. We compared the results of an immunofluorescence (IF) test, a haemagglutination (HA) test, and an enzyme-linked immunosorbent assay (ELISA) for the diagnosis of T. cruzi infections in a large population-based survey in central Brazil using blood eluates from filter-paper and venous blood samples. The sensitivities of the tests on eluates, compared with results on serum samples, were low: ELISA (78. 1%), IF (69.2%) and HA (64.6%). The level of agreement between the tests on eluates was very poor, with the best co-positivity for IF and ELISA. Both the positive and negative predictive values of the three tests on eluates were similar (around 96%) to those for sera. Higher co-positivity values were obtained for the three tests on sera. The implications of these results are discussed in relation to blood screening, routine medical practice, sero-epidemiological surveys, and the follow-up of patients admitted to therapeutic trials. | pt_BR |
| dc.identifier.citation | ZICKER, F.; SMITH, P. G.; LUQUETTI, A. O.; OLIVEIRA, O. S. Mass screening for Trypanosoma cruzi infections using the immunofluorescence, ELISA and haemagglutination tests on serum samples and on blood eluates from filter-paper. Bulletin of the World Health Organization, Bethesda, v. 68, n. 4, p. 465-471, 1990. | pt_BR |
| dc.identifier.issn | 0042-9686 | |
| dc.identifier.issn | e- 1564-0604 | |
| dc.identifier.uri | http://repositorio.bc.ufg.br/handle/ri/14895 | |
| dc.language.iso | eng | pt_BR |
| dc.publisher.country | Estados unidos | pt_BR |
| dc.publisher.department | Instituto de Patologia Tropical e Saúde Pública - IPTSP (RG) | pt_BR |
| dc.rights | Acesso Aberto | pt_BR |
| dc.title | Mass screening for Trypanosoma cruzi infections using the immunofluorescence, ELISA and haemagglutination tests on serum samples and on blood eluates from filter-paper | pt_BR |
| dc.type | Artigo | pt_BR |