A evolução da química medicinal no Brasil: avanços nos 40 anos da Sociedade Brasileira de Química
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2017
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MEDICINAL CHEMISTRY PROGRESS IN BRAZIL: ADVANCES IN THE 40 YEARS OF THE BRAZILIAN CHEMICAL
SOCIETY. Medicinal Chemistry includes the invention, discovery, design, identification, and interpretation of the molecular
mechanism of action of biologically active compounds. In addition to the discovery of bioactive molecules, Medicinal Chemistry
investigates drug metabolism and the relationships between chemical structure and biological activity. The advances achieved in the
20th century have significantly contributed to the better understanding of pathophysiological processes as well as the development
of new, safer and more effective drugs for many diseases. In this article, we review the evolution of Medicinal Chemistry in Brazil
during the last 40 years and evaluate the impact of the Brazilian contributions in the international context. The analyzed data revealed
that Medicinal Chemistry research in Brazil has increased exponentially in the last two decades, the research groups became more
well-distributed across the Brazilian regions and our scientific contributions have significant impact in the main journals of the field.
Therefore, aiming at evolving steadily and striving for excellence in drug discovery and development, we shall focus on national and
international collaborations and investment in translational research, as well.
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Medicinal Chemistry, Brazil, Progress, Evolution
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AMARAL, Antonia Tavares da; ANDRADE, Carolina Horta ; KUMMERLE, Arthur E.; GUIDO, e Rafael V. C. A evolução da química medicinal no Brasil: avanços nos 40 anos da Sociedade Brasileira de Química. Química Nova, Campinas, v. 40, p. 694-700, 2017. DOI: 10.21577/0100-4042.20170075. Disponível em: https://www.scielo.br/j/qn/a/4VfxtNHmHmpPZnkNYXzYbZK/?lang=pt. Acesso em: 11 nov. 2024.