Total knee arthroplasty in a patient diagnosed with ochronosis: case report

Abstract

Ochronosis is a rare autosomal recessive disorder caused by a deficiency in homogentisic acid oxidase, leading to significant orthopedic challenges, particularly in knee joints. This progressive pathology often necessitates arthroplasty, which can be complicated by the disease's severe joint degeneration. We report the case of a 72-year-old female who underwent successful total knee arthroplasty on both knees, with outcomes validated through three-dimensional kinematic assessments, medical records, and patient satisfaction surveys.