Efficacy of sodium hypochlorite and chlorhexidine against Enterococcus faecalis - a systematic review
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Data
2008
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Resumo
T
he efficacy of the sodium hypochlorite (NaOCl) and chlorhexidine (CHX) on Enterococcus faecalis was evaluated by systematic
review and meta-analysis. The search strategies included search in electronic biomedical journal databases (MEDLINE, EMBASE,
CENTRAL) and handsearching records, using different matches of keywords for NaOCl, CHX and Enterococcus faecalis. From 41
in vivo studies, 5 studies met the inclusion criteria. In a sample containing 159 teeth, E. faecalis was detected initially in 16 (10%)
teeth by polymerase chain reaction (PCR) and 42 (26.4%) teeth by microbial culture techniques. After root canal disinfection, this
species was observed in 11 (6.9%) teeth by PCR and 12 (7.5%) teeth by culture. Risk differences of included studies were combined
as generic inverse variance data type (Review Manager Version 5.0 – Cochrane Collaboration, http://www.cc-ims.net, accessed 15
May 2008), taking into account the separate tracking of positive and negative cultures/PCR. The level of statistical significance was
set at p<0.05. In conclusion, NaOCl or CHX showed low ability to eliminate E. faecalis when evaluated by either PCR or culture
techniques.
Descrição
Palavras-chave
E. faecalis, Systematic review, Sodium hypochlorite, Irrigating solutions, Chlorhexidine
Citação
ESTRELA, Carlos et al. Efficacy of sodium hypochlorite and chlorhexidine against Enterococcus faecalis -
a systematic review. Journal of Applied Oral Science, Bauru, v. 16, n. 6, p. 364-368, 2008.