Uso de probióticos em dermocosméticos destinados ao tratamento de pele acneica

Abstract

Despite being a very prevalent and common skin condition, acne is still a disease whose pathophysiological mechanisms are not very well defined and fully understood. Its conventional therapeutic line presents challenges in its effectiveness and efficiency, in addition to promoting many adverse effects, directly impacting the quality of life of affected individuals. Therefore, new alternatives have been investigated. One of the areas that has been explored to better understand the complexity of acne involves the microbiota and its dysbiosis process. Recent studies point to the importance of maintaining homeostasis of the skin's microbiota for better management of the clinical manifestations of the disease. Among the new therapeutic alternatives that act on the microbiota are topical probiotics. Evidence shows that these have inhibitory activity on acne mechanisms and present a clinical-therapeutic alternative in the management of acne by preventing the growth of pathogenic bacteria and the development of inflammatory processes. However, the therapeutic scenario of topical probiotics is still evolving, requiring greater exploration and clarification on the subject through the promotion of studies that demonstrate better clinical-therapeutic capacity.