A comparative study on active and passive epidemiological surveillance for dengue in five countries of Latin America

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dc.creatorSarti, Elsa
dc.creatorL'Azou, Maïna
dc.creatorMercado, Marcela
dc.creatorKuri Morales, Pablo
dc.creatorSiqueira Júnior, João Bosco
dc.creatorSolis, Erick
dc.creatorNoriega, Fernando
dc.creatorOchiai, R. Leon
dc.date.accessioned2025-01-22T11:49:24Z
dc.date.available2025-01-22T11:49:24Z
dc.date.issued2016
dc.description.abstractBackground: Dengue is a notifiable infectious disease in many countries, but under-reporting of cases to National Epidemiological Surveillance Systems (NESSs) conceals the true extent of the disease burden. The incidence of dengue identified in a cohort study was compared with those reported to NESSs. Methods: A randomized, placebo-controlled study was undertaken in Brazil, Colombia, Honduras, Mexico, and Puerto Rico to assess the efficacy of a tetravalent dengue vaccine (CYD-TDV) in children aged 9–16 years. The incidence of dengue in the placebo group was compared with that reported to NESSs in a similar age group (10–19 years) from June 2011 to April 2014. Results: Three thousand six hundred and fifteen suspected dengue cases were identified in the study over 13 527 person-years of observation. The overall incidence of confirmed dengue was 2.9 per 100 person-years (range 1.5 to 4.1 per 100 person-years). In the NESSs combined, over 3.2 million suspected dengue cases were reported during the same period, corresponding to over 1 billion person years of observation. The incidence of confirmed dengue reported by the NESSs in the same locality where the study took place was 0.286 per 100 person-years across Brazil, Colombia, and Mexico (range 0.180 to 0.734 per 100 person-years). The incidence of confirmed dengue was 10.0-fold higher in the study than that reported to NESSs in the same localities (range 3.5- to 19.4-fold higher). Conclusions: There is a substantial under-reporting of dengue in the NESSs. Understanding the level of under-reporting would allow more accurate estimates of the dengue burden in Latin America.
dc.identifier.citationSARTI, Elsa et al. A comparative study on active and passive epidemiological surveillance for dengue in five countries of Latin America. International Journal of Infectious Diseases, Hamilton, v. 44, p. 44-49, 2016. DOI: 10.1016/j.ijid.2016.01.015. Disponível em: https://www.sciencedirect.com/science/article/pii/S1201971216000163?via%3Dihub. Acesso em: 20 jan. 2025.1201-9712.
dc.identifier.doi10.1016/j.ijid.2016.01.015
dc.identifier.issne- 1878-3511
dc.identifier.issn1201-9712
dc.identifier.urihttp://repositorio.bc.ufg.br//handle/ri/26425
dc.language.isoeng
dc.publisher.countryCanada
dc.publisher.departmentInstituto de Patologia Tropical e Saúde Pública - IPTSP (RMG)
dc.rightsAcesso Aberto
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectDengue
dc.subjectFlavivirus
dc.subjectSurveillance
dc.subjectEpidemiology
dc.subjectSouth America
dc.titleA comparative study on active and passive epidemiological surveillance for dengue in five countries of Latin America
dc.typeArtigo

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