Functional impairments in white matter syndrome of neuropsychiatric systemic lupus erythematosus are similar to those observed in patients with multiple sclerosis
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Data
2012
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Resumo
Objective: In order to compare white matter syndrome of neuropsychiatric systemic lupus erythematosus (NPSLE) and multiple sclerosis
(MS), an assessment on demographic, medical history, and clinical data was proposed. Methods: Sixty-four patients with NPSLE and 178
with MS answered a questionnaire and were evaluated regarding functional system, expanded disability status scale (EDSS), Beck depres-
sion inventory (BDI), and Beck anxiety inventory (BAI). Results: The prevalence of autoimmune diseases and altered consciousness was simi-
lar in both groups, however it was higher than in the general population. Systemic signs and symptoms occurred from 2.9 to 61.9% of the MS
cases, while neurological signs and symptoms occurred in 9.4 to 76.4% of the NPSLE ones. The motor, visual, and mental systems were the
most affected in both diseases. The BDI in NPSLE had higher scores and the BAI in MS. Conclusions: The functional impairments in NPSLE
were similar to those of MS, although greater impairment of the functional systems of cerebellar, sensitivity, and sphincters occurred in MS
cases, and greater symptoms of depression, anxiety, and headache also occurred in it.
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Lupus erythematosus, Anxiety, Systemic, Multiple sclerosis, Medical records, Neurologic examination, Depression, Lúpus eritematoso sistêmico, Esclerose múltipla, Ansiedade, Registros médicos, Depressão, Exame neurológico
Citação
DINIZ, D. S.c et al. Funcional imparement in white matter syndrome of neuropsychiatric systemic lupus eruthematosus are similar to those observed in patients with multiple sclerosis. Arquivos de Neuro-Psiquiatria, São Paulo, v. 70, n. 10, p. 769-773, 2012.