Phage display e sua aplicação em medicina veterinaria
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Data
2015
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Resumo
The phage display technology was first described in 1985. Since that time, different
recombinant molecules, such as small peptides or antibody fragments are displayed
on the surface of filamentous phage proteins, expanding greatly the applications of
this technique. Different prospection methods allow the isolation and
characterization, whether in vitro and in vivo, of peptides that are reactive to a wide
range of biological targets. This paper aims to review the principles of the phage
display technique and its potential as an important tool for the characterization of
biomolecules and their applications in the diagnosis and therapy of veterinary
diseases.
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Palavras-chave
Bibliotecas de peptídeos, Terapêutica, Doenças veterinárias, Diagnóstico, Diagnosis, Veterinary diseases, Peptide library, Therapy
Citação
ALMEIDA, Greyciele Rodrigues de et al. Phage display e sua aplicação em medicina veterinaria. Enciclopédia Biosfera, Goiânia, v. 11, n. 22, p. 2366-2382, 2015.