Investigação da ocorrência do vírus Chikungunya (CHIKV) em indivíduos sintomáticos no município de Goiânia-Goiás
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Data
2021-05-20
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Universidade Federal de Goiás
Resumo
Chikungunya is an arbovirosis transmitted by mosquitoes of the genus Aedes, and its etiological agent is the Chikungunya virus (CHIKV). The viral infection can be divided into acute and chronic phases, usually has an incubation period of 2 to 10 days.
For laboratory diagnosis of CHIKV, methods such as isolation of the virus in cell culture, serological methods and molecular methods can be used. Since the introduction of the virus in Brazil until 2019, 589,076 probable cases were reported and 495 confirmed deaths, in Goiás between the years 2015 and 2020, 1591 cases were reported. This study aimed to investigate the occurrence of the chikungunya virus in a symptomatic population treated in the public health system in Goiânia. The samples were collected in health units and sent to LabViCC. After extraction of the viral RNA, molecular investigation was performed by RT-PCR in real time. In total 140 samples were analyzed, it was observed that all of them tested negative for the presence of CHIKV. The data obtained in the present investigation reinforce the need to establish strategies for continuous surveillance and monitoring, helping to better understand the role of CHIKV in our region. Studies like this are extremely important in the epidemiological description of the disease, especially in areas endemic to arboviruses, where the simultaneous circulation of Zika, Dengue and Chikungunya can occur.
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Vigilância, Vírus Chikungunya, Detecção molecular, RT-PCR tempo real, Surveillance, Chikungunya virus, Molecular detection, Real-time RT-PCR
Citação
LEÃO NETO, Esther Ferreira. Investigação da ocorrência do vírus Chikungunya (CHIKV) em indivíduos sintomáticos no município de Goiânia-Goiás. 2021. 41 f. Trabalho de Conclusão de Curso (Graduação) – Faculdade de Farmácia, Universidade Federal de Goiás, Goiânia, 2021.