Influence of Beta-2-Adrenergic receptor Gln27Glu polymorphism on the autonomic heart rate modulation in young sedentary and physically active women
| dc.creator | Rebelo, Ana Cristina Silva | |
| dc.creator | Melo, Aryanne Batista Soares de | |
| dc.creator | Salviati, Mariana Rodrigues | |
| dc.creator | Verlengia, Rozangela | |
| dc.creator | Vale, Arthur Ferreira do | |
| dc.creator | Nogueira, Yanley Lucio | |
| dc.creator | Tamburús, Nayara Yamada | |
| dc.creator | Kunz, Vandeni Clarice | |
| dc.creator | Silva, Ester da | |
| dc.date.accessioned | 2018-10-30T11:28:11Z | |
| dc.date.available | 2018-10-30T11:28:11Z | |
| dc.date.issued | 2015 | |
| dc.description.resumo | Background: Studies have shown an interaction between the autonomic heart rate (HR) modulation and genetic polymorphisms. Nevertheless, it is yet unclear how a particular genetic polymorphism may determine a pattern of autonomic HR control, especially regarding the role of physical exercise. The objective was to investigate the influence of of Beta-2- Adrenergic (β2-AR) Gln27Glu polymorphisms and exercise on HRV of young Brazilian women. Methods: The group was selected as Sedentary Group (SG; n = 88) and physically Active Group (AG; n = 99). The β2-AR polymorphisms were analyzed using PCR-RFLP. The amplicons were subjected to electrophoresis on a 10% acrylamide gel and stained with ethidium bromide. The HR was registered in real time for 15 minutes, in the supine-position. The heart rate variability (HRV) was analysed using Shannon’s entropy (SE), conditional entropy (complexity index [CInd] and normalized CInd [NCI]), and symbolic analysis (0V%, 1V%, 2LV%, and 2ULV%). Statistical analysis: Analysis of variance (ANOVA) with Fisher's Least. Results: AG presented higher values for SE and 2ULV%, and lower values for 0V% when compared to SG (p<0.05). There was no significant difference of any index among genotypes both from the complexity and symbolic analysis. The interaction between genotype and exercise did not significantly affect HRV. Conclusion: These results do not support the concept that the β2-AR Gln27Glu polymorphisms affects the HRV indexes in physically active or sedentary women. | pt_BR |
| dc.identifier.citation | REBELO, Ana Cristina Silva. Influence of Beta-2-Adrenergic receptor Gln27Glu polymorphism on the autonomic heart rate modulation in young sedentary and physically active women. American Journal of BioScience, New York, v. 3, n. 5, p. 190-196, 2015. | pt_BR |
| dc.identifier.doi | 10.11648/j.ajbio.20150305.15 | |
| dc.identifier.issn | 2330-0159 | |
| dc.identifier.issn | e- 2330-0167 | |
| dc.identifier.uri | http://repositorio.bc.ufg.br/handle/ri/16290 | |
| dc.language.iso | eng | pt_BR |
| dc.publisher.country | Estados unidos | pt_BR |
| dc.publisher.department | Instituto de Ciências Biológicas - ICB (RG) | pt_BR |
| dc.rights | Acesso Aberto | pt_BR |
| dc.subject | β 2 -Adrenergic polymorphism | pt_BR |
| dc.subject | Women | pt_BR |
| dc.subject | Exercise | pt_BR |
| dc.subject | Heart rate variability | pt_BR |
| dc.subject | Non-linear analysis | pt_BR |
| dc.title | Influence of Beta-2-Adrenergic receptor Gln27Glu polymorphism on the autonomic heart rate modulation in young sedentary and physically active women | pt_BR |
| dc.type | Artigo | pt_BR |