Antioxidant activity of a standardized extract of Byrsonima japurensis A. Juss. (Malpighiaceae) stem bark
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Data
2013-07
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Resumo
An infusion of 5% Byrsonima japurensis stem bark, an Amazonian medicinal plant, presented
anti-inflammatory, anti-hyperalgesic, antiplatelet and antiulcer activity in a previous study. In this study,
pharmacognostical parameters for this raw material were determined and the technological
characterization of the infusion was performed, concurrently with the assessment of their antioxidant
potential. The analysis of the raw material and the crude extract was done using pharmacopoeial and
non-pharmacopeial methods. The antioxidant potential was evaluated by diphenylpicrylhydrazyl (DPPH•),
2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS•+) and nitric oxide (NO•) radical scavenger
assays. The raw material presented a mean size of particles of 318.30 ± 1.65 µm, ash content of 3.39 ± 0.04
g%, 10.32 ± 0.09 g% loss on drying and 12.23 ± 0.17 g% of matter extractable by water. The extract
obtained by infusion of 5% of plant drug is rich in polyphenol compounds (50.69 ± 3.64 mg GAE/g) with
appreciable flavonoid content (2.38 ± 1.15 mg quercetin/g). This extract showed expressive antioxidant
activity, which was significantly better than ascorbic acid and Trolox in both DPPH and ABTS radical
scavengers tests (p < 0.05), which is closely related to its previously detected anti-inflammatory activity
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Infusion, Phenol compounds, Nitric oxide
Citação
GUILHON-SIMPLICIO, Fernanda et al. Antioxidant activity of a standardized extract of Byrsonima japurensis A. Juss. (Malpighiaceae) stem bark. Journal of Medicinal Plant Research, v. 7, n. 26, p. 1926-1930, July 2013.