New surgery technique for refractory macular hole guided by intraoperative OCT: free internal limiting membrane flap and autologous blood clot

Resumo

Background Present a new surgical technique which involves using pars plana vitrectomy (PPV) combined with a free internal limiting membrane (ILM) flap anchored by an intraoperatively obtained blood clot, assisted by intraoperative optical coherence tomography (i-OCT). Methods This is a prospective interventional non-comparative study with three cases of recurrent or refractory macular hole treated with a new surgical technique using autologous blood clot obtained from the retinal vessels. Results This study included 3 eyes of 3 patients. All patients were previously treated with a PPV and internal limiting membrane peeling. One week post-operatively, all operated eyes showed closure of the macular hole. No complica tions secondary to the surgical technique occurred. Conclusion This is a small case series that obtained anatomical success in the macular hole closure with a reproduc ible technique involving the use of i-OCT to position a free ILM flap, anchored by a blood clot obtained from per oper atory retinal bleeding. Further controlled research needs to be done to prove the efficacy.

Descrição

Citação

BASTOS, Thais Marino de Azeredo et al. New surgery technique for refractory macular hole guided by intraoperative OCT: free internal limiting membrane flap and autologous blood clot. International Journal of Retina and Vitreous, Berlin, v. 11, e60, 2025. DOI: 10.1186/s40942-025-00681-6. Disponível em: https://link.springer.com/article/10.1186/s40942-025-00681-6. Acesso em: 22 abr. 2026.