Avaliação histológica de fígado, rim, tireóide, paratireóide e osso de suínos em terminação submetidos a diferentes dietas
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Data
2008-12
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Editor
José Henrique Stringhini
Resumo
The present experiment aimed to evaluate histological
changes in hepatic, renal, thyroid, parathyroid and
metacarpian bone tissues of pigs submitted to diets without
micro minerals and vitamins, reduced inorganic phosphorus levels and phytase addition in two restriction times. Forty
eight 105-days old (66.15±0.14 kg) female pigs received
experimental diets with corn, soybean and wheat meal. The
animals were randomly distributed in six groups: standard diets (T1); composed of corn, soybean meal and wheat
meal; standard ration without micro mineral and vitamin
supplement (T2); T2 ration with phytase (T3); T2 ration
reducing 1/3 of inorganic phosphorus with phytase (T4);
T2 ration reduced 2/3 of inorganic phosphorus with phytase
(T5); and T2 ration with complete reduction of inorganic
phosphorus with phytase (T6). The experiment was carried
out in two phases: Phase 1. 24 animals, 35 days of restriction
and slaughter at 150 days of age (106.65 kg), and Phase 2,
24 animals, 60 days of restriction and slaughter at 175 days
of age (123.87 kg). At slaughter, samples of liver, kidney,
thyroid, parathyroid and metacarpian bone were collected
from all animals. The samples were fixed in 10% buffered
formaldehyde and stained by hematoxilin and eosin (HE).
The Mallory’s trichrome stain was used in bone sections.
Kidney histopathological evaluation showed interstitial
nephritis in 37 animals (77%). Mononuclear inflammatory
infiltrated was observed focally on liver of 15 animals
(31.25%). Treatments didn’t promote histopathological
changes in thyroid and parathyroid glands. The metacarpian
bone microscopy showed low osteochondrosis in
animals of different treatments and phases. However, in
experimental time, clinic signs of bone metabolic disease
and osteochondrosis were not verified. Phytase addition was
efficient to provide phytic phosphorus in the diet, since no
macro or microscopic lesions characterizing phosphorus
deficiency in the bone samples were present.
Descrição
Palavras-chave
Alterações histológicas, Fitase, Restrição de fósforo, Vitaminas, Microminerais, Histopathologic changes, Micro minerals, Phytase, Phosphorus restriction, Vitamins
Citação
MATOS, Moema Pacheco Chediak; MIGUEL, Marina Pacheco; MOURA, Veridiana Maria Brianezi Dignani; SOBESTIANSKY, Jurij; BRITO, Luiz Augusto Batista. Avaliação histológica de fígado, rim, tireóide, paratireóide e osso de suínos em terminação submetidos a diferentes dietas. Ciência Animal Brasileira, Goiânia, v. 9, n. 4, p.1128-1137, out./dez. 2008. Disponível em: < https://www.revistas.ufg.br/vet/article/view/1573/4377>.