Kopsanone and N-oxide isolated from Aspidosperma macrocarpon Mart. (Apocynaceae) leaves and their MAO-A inhibitory activity

Peixoto, Matheus Ardenghi; Kato, Lucilia; Oliveira, Cecília Maria Alves de; Vaz, Boniek Gontijo; Silva, Cleuza Conceição da; Klein Júnior, Luiz Carlos; Passos, Carolina dos Santos; Henriques, Amelia Teresinha; Bannwart, Geanderson; Santin, Silvana Maria de Oliveira

Kopsanone and N-oxide isolated from Aspidosperma macrocarpon Mart. (Apocynaceae) leaves and their MAO-A inhibitory activity

Data

2021

Autores

Peixoto, Matheus Ardenghi

Kato, Lucilia

Oliveira, Cecília Maria Alves de

Vaz, Boniek Gontijo

Silva, Cleuza Conceição da

Klein Júnior, Luiz Carlos

Passos, Carolina dos Santos

Henriques, Amelia Teresinha

Bannwart, Geanderson

Santin, Silvana Maria de Oliveira

Resumo

Aspidosperma macrocarpon Mart., popularly known as ‘guatambu’ or ‘peroba’, is found from North American (Mexico) to South American (Argentina) continents and in Brazil. Two indole alkaloids were isolated from leaves of A. macrocarpon, kopsanone (1) and unreported N(4)-oxide-kopsanone (2).

Palavras-chave

Aspidosperma macrocarpon, Acetylcholinesterase inhibitors, β-carboline alkaloids

Citação

PEIXOTO, Matheus Ardenghi et al. Kopsanone and N-oxide isolated from Aspidosperma macrocarpon Mart. (Apocynaceae) leaves and their MAO-A inhibitory activity. Natural Product Research, Abingdon, v. 35, n. 23, p. 5465-5469, 2021. DOI: 10.1080/14786419.2020.1782402. Disponível em: https://www.tandfonline.com/doi/full/10.1080/14786419.2020.1782402. Acesso em: 28 ago. 2023.