Trans-sialidase inhibition assay, a highly sensitive and specific diagnostic test for Chagas' disease

Resumo

For the diagnosis of Chagas’ disease, the trans-sialidase inhibition assay was able to resolve the results for samples with borderline results, to detect as positive 60% of samples that were negative by conventional serology, and to discriminate idiopathic from chagasic megaviscera or cardiopathy. No cross-reaction with sera from patients with other diseases was observed.

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Citação

BUCHOVSKY, A. S.; CAMPETELLA, O.; RUSSOMANDO, G.; FRANCO, L.; ODDONE, R.; CANDIA, N.; LUQUETTI, A.; CAPPA, S. M. Gonzales; LEGUIZAMON, M. S. Trans-sialidase inhibition assay, a highly sensitive and specific diagnostic test for Chagas' disease. Clinical and Diagnostic Laboratory Immunology, Washington, v. 8, n.1, p. 187-189, Jan. 2001.