Physicochemical/photophysical characterization and angiogenic properties of Curcuma longa essential oil
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2016
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This study analyzed the physicochemical and photophysical properties of essential oil of Curcuma longa
and its angiogenic potential. The results showed that curcumin is the main fluorescent component present
in the oil, although the amount is relatively small. The experimental chorioallantoic membrane model was
used to evaluate angiogenic activity, showing a significant increase in the vascular network of Curcuma
longa and positive control groups when compared to the neutral and inhibitor controls (P <0.05), but no
significant difference was found between Curcuma longa essential oil and the positive control (P >0.05).
Histological analysis showed extensive neovascularization, hyperemia and inflammation in the positive
control group and Curcuma longa when compared to other controls (P <0.05), characteristic factors of the
angiogenesis process. In conclusion, Curcuma longa oil showed considerable proangiogenic activity and
could be a potential compound in medical applications.
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Angiogenic activity, Pphysicochemical, Curcumin, essential oil
Citação
ARAÚJO, Lilhian A. et al. Physicochemical/photophysical characterization and angiogenic properties of Curcuma longa essential oil. Anais da Academia Brasileira de Ciências, Rio de Janeiro, v. 88, n. 3, p. 1889-1897, 2016. Suplemento. DOI: 10.1590/0001-3765201620150600. Disponível em: https://www.scielo.br/j/aabc/a/TDTpMWdS5gmNFz6xf8FyG7P/?lang=en. Acesso em: 5 maio 2023.