25I-NBOH: a new potent serotonin 5-HT2A receptor agonist identified in blotter paper seizures in Brazil

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dc.creatorArantes, Luciano Chaves
dc.creatorFerrari Júnior, Ettore
dc.creatorSouza, Luciano Figueiredo de
dc.creatorCardoso, Andriele Costa
dc.creatorAlcantara, Thaynara Lino Fernandes
dc.creatorLiao, Luciano Morais
dc.creatorMachado, Yuri
dc.creatorLordeiro, Rogério Araújo
dc.creatorCoelho Neto, José
dc.creatorAndrade, Ana Flávia Belchior de
dc.date.accessioned2024-03-05T15:09:46Z
dc.date.available2024-03-05T15:09:46Z
dc.date.issued2017-02-16
dc.description.abstractA new potent serotonin 5-HT2A receptor agonist was identified in blotter papers by several state level forensic laboratories in Brazil. The 25I-NBOH is a labile molecule, which fragments into 2C-I when analyzed by routine seized material screening gas chromatography (GC) methods. GC–mass spectrometry (MS), liquid chromatography–quadrupole time-of-flight-MS, and Fourier transform infrared and nuclear magnetic resonance analyses were performed to complete molecular characterization. Individual doses range from 300 to 1000 lg. Despite its being a potent 5-HT2A receptor agonist, 25I-NBOH is neither registered in the United Nations Office on Drugs and Crime (UNODC) nor classified as a scheduled substance in most countries. Sweden and Brazil seem to be the only countries to control 25I-NBOH. To our knowledge, this is the first scientific report dealing with identification of 25I-NBOH in actual seizures.
dc.identifier.citationARANTES, Luciano Chaves et al. 25I-NBOH: a new potent serotonin 5-HT2A receptor agonist identified in blotter paper seizures in Brazil. Forensic Toxicology, Tokyo, v. 35, p. 408-414, 2017. DOI: 10.1007/s11419-017-0357-x. Disponível em: https://link.springer.com/article/10.1007/s11419-017-0357-x. Acesso em: 16 fev. 2024.
dc.identifier.doi10.1007/s11419-017-0357-x
dc.identifier.issne- 1860-8973
dc.identifier.issn1860-8965
dc.identifier.urihttp://repositorio.bc.ufg.br//handle/ri/24475
dc.language.isoeng
dc.publisher.countryOutros
dc.publisher.departmentInstituto de Química - IQ (RMG)
dc.rightsAcesso Aberto
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject25I-NBOH
dc.subjectNBOH
dc.subjectPhenethylamine derivatives
dc.subjectNPS
dc.subject5-HT2A receptor agonist
dc.title25I-NBOH: a new potent serotonin 5-HT2A receptor agonist identified in blotter paper seizures in Brazil
dc.typeArtigo

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