Avaliação da atividade antinociceptiva do extrato hidroalcóolico das folhas e galhos de croton sacaquinha croizat (euphorbiaceae)
Carregando...
Data
2010-06
Autores
Título da Revista
ISSN da Revista
Título de Volume
Editor
Resumo
The objective of this study was to evaluate the antinociceptive activity and the effect on leukocytes
migration of hidroalcoolic extract (EHA) obtained from Croton sacaquinha branches and barks.
For this purpose were utilized male Swiss mice submitted to the acetic acid-induced writhes
test, formalin test, hot-plate test and the carragenaan induced peritonitis test. The EHA showed
an antinociceptive activity in the acetic acid-induced writhes and in the 2 nd phase of formalin
test also reducing the leukocytes migration. The extract was ineffective in the other tests. These
results suggest an antinociceptive activity of the plant which could be related to anti-inflammatory
mechanisms. This work may confirm the use of C. sacaquinha in the popular medicine for its
analgesic properties.
Descrição
Palavras-chave
Plantas medicinais, Anti-inflamatório, Analgésico, Medicinal plant, Anti-inflammatory, Analgesic
Citação
COSTA-E-SOUSA, Ricardo H. et al. Avaliação da atividade antinociceptiva do extrato hidroalcóolico das folhas e galhos de croton sacaquinha croizat (euphorbiaceae). Revista de Ciências da Vida, Rio de Janeiro, v. 30, n. 1, p. 65-75, jan./jun. 2010.