Synthesis of potential anti-Trypanosoma cruzi azole-naftifine analogues by azide–alkyne click reaction

Resumo

Twenty novel azole-naftifine analogues were obtained using azide–alkyne click reaction. Five of them were more potent than the positive control naftifine revealing an unprecedented antiproliferative effects against Trypanosoma cruzi.

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Citação

ZACCHIA, Carlos Henrique Callegario et al. Synthesis of potential anti-Trypanosoma cruzi azole-naftifine analogues by azide–alkyne click reaction. Mendeleev Communications, Amsterdam, v. 28, p. 195-197, 2018. DOI: 10.1016/j.mencom.2018.03.029. Disponível em: https://www.sciencedirect.com/science/article/abs/pii/S0959943618300786. Acesso em: 27 nov. 2023.