Tissue reaction and anti-biofilm action of new biomaterial composed of latex from Hancornia speciosa Gomes and silver nanoparticles
Nenhuma Miniatura disponível
Data
2020
Título da Revista
ISSN da Revista
Título de Volume
Editor
Resumo
In this work, the natural latex extracted from Harconia speciosa was
incorporated with silver nanoparticles (AgNP) to compose a functional biomaterial
associating the intrinsic angiogenic activity of the latex and the antimicrobial activity of
AgNP. Tissue reaction after subcutaneous implantation in dorsum of rats of membranes
without AgNP and with 0.05%, 0.4% AgNP was compared at 3, 7 and 25 days. No
statistically signifi cant difference in the tissue response of the different biomaterials
was observed, indicating that AgNP did not interfere with the infl ammatory reaction (p
> 0.05) or with the angiogenic activity of latex. Biomembranes were also tested against
bacterial biofi lm formation by Staphylococcus aureus and the antimicrobial activity of
the new biomaterial can be found with bacteria crenation (0.05% AgNP) and no biofi lm
deposition (0.4% AgNP). Therefore, this biomaterial has interesting properties for the
tissue repair process and may be feasible for future applications as dressing
Descrição
Palavras-chave
Antimicrobial activity, Wound dressings, Biomembrane, Silver nanoparticle, Biocompatibility, Inflammation
Citação
BONETE, Jéssica M.; SILVA, Guilherme D.; GUIDELLI, Éder J.; GONÇALVES, Pablo J.; ALMEIDA, Luciane M.; BAFFA, Oswaldo; KINOSHITA, Angela. Tissue reaction and anti-biofilm action of new biomaterial composed of latex from Hancornia speciosa Gomes and silver nanoparticles. Anais da Academia Brasileira de Ciências, Rio de Janeiro, v. 92, n. 4, e20191584, 2020. DOI: 10.1590/0001-3765202020191584. Disponível em: https://www.scielo.br/j/aabc/a/w8vqvyHYRPmLb49ZxT9MPPf/?lang=en. Acesso em: 5 maio 2023.