Molluscicidal activity of polyvinylpyrrolidone (PVP)-functionalized silver nanoparticles to Biomphalaria glabrata: implications for control of intermediate host snail of Schistosoma mansoni

Página do item simplificado
dc.creatorAraujo, Paula Sampaio
dc.creatorCaixeta, Maxwell Batista
dc.creatorBrito, Rafaella da Silva
dc.creatorGonçalves, Bruno Bastos
dc.creatorSilva, Sueli Maria da
dc.creatorLima, Emilia Celma de Oliveira
dc.creatorSilva, Luciana Damacena
dc.creatorBezerra, José Clecildo Barreto
dc.creatorRocha, Thiago Lopes
dc.date.accessioned2023-10-26T12:50:10Z
dc.date.available2023-10-26T12:50:10Z
dc.date.issued2020
dc.description.abstractSilver nanoparticles (Ag NPs) have been applied in several commercial products due to their antimicrobial properties, while their molluscicide properties, mode of action and toxicity to snail species remain unclear. In this study, the comparative toxicity of polyvinylpyrrolidone (PVP)-functionalized Ag NPs and their dissolved counterpart (Ag ions) was analyzed during the early developmental stages of the freshwater snail Biomphalaria glabrata, intermediate host of Schistosoma mansoni. Ag NPs were synthesized and characterized by multiple techniques, and the snail embryotoxicity was analyzed in terms of mortality, hatching, developmental stages and morphological alterations, while the acute toxicity to newly-hatched snails was analyzed by mortality and behavioral impairments. Results showed that both Ag forms induced mortality, hatching delay and morphological alterations (especially hydropic abnormalities) in snail embryos in a concentration and exposure time dependent patterns. Ag NPs showed low embryotoxic effects and similar toxicity for newly-hatched snails when compared to their dissolved counterparts, indicating that the nanotoxicity was dependent of snail developmental stages. The knowledge about the Ag NP toxicity to different early development stages of B. glabrata contributes to its potential use as molluscicide and control of neglected tropical diseases, including schistosomiasis.
dc.identifier.citationARAÚJO, Paula Sampaio et al. Molluscicidal activity of polyvinylpyrrolidone (PVP)-functionalized silver nanoparticles to Biomphalaria glabrata: implications for control of intermediate host snail of Schistosoma mansoni. Acta Tropica, Amsterdam, v. 211, e105644-8, 2020. DOI: 10.1016/j.actatropica.2020.105644. Disponível em: https://www.sciencedirect.com/science/article/abs/pii/S0001706X20300620?via%3Dihub. Acesso em: 27 set. 2023.
dc.identifier.doi10.1016/j.actatropica.2020.105644
dc.identifier.issne- 1873-6254
dc.identifier.issn0001-706X
dc.identifier.urihttps://www.sciencedirect.com/science/article/abs/pii/S0001706X20300620?via%3Dihub
dc.language.isoeng
dc.publisher.countryHolanda
dc.publisher.departmentInstituto de Química - IQ (RMG)
dc.rightsAcesso Restrito
dc.subjectEmbryotoxicity
dc.subjectMolluscicide
dc.subjectNanomaterials
dc.subjectNanotoxicity
dc.subjectSchistosomiasis
dc.titleMolluscicidal activity of polyvinylpyrrolidone (PVP)-functionalized silver nanoparticles to Biomphalaria glabrata: implications for control of intermediate host snail of Schistosoma mansoni
dc.typeArtigo

Arquivos

Licença do Pacote
Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Baixar

Coleções

IQ - Artigos publicados em periódicos