Y chromosome microdeletions in brazilian fertility clinic patients

Página do item simplificado
dc.creatorArruda, Jalsi Tacon
dc.creatorBordin, Bárbara Mariotto
dc.creatorSantos, P. R.
dc.creatorMesquita, Wyara Elanne de Jesus Castro
dc.creatorSilva, R. C. P. C.
dc.creatorMaia, M. C. S.
dc.creatorApprobato, Mario Silva
dc.creatorFlorêncio, Rodopiano de Souza
dc.creatorAmaral, Waldemar Naves do
dc.creatorRocha Filho, M. A.
dc.creatorMoura, Katia karina Verolli de Oliveira
dc.date.accessioned2019-08-20T15:54:37Z
dc.date.available2019-08-20T15:54:37Z
dc.date.issued2007
dc.description.abstractMicrodeletions in Yq are associated with defects in spermatogenesis, while those in the AZF region are considered criti- cal for germ cell development. We examined microdeletions in the Y chromosomes of patients attended at the Laboratory of Human Repro- duction of the Clinical Hospital of the Federal University of Goiás as part of a screening of patients who plan to undergo assisted reproduc- tion. Analysis was made of the AZF region of the Y chromosome in men who had altered spermograms to detect possible microdeletions in Yq. Twenty-three patients with azoospermia and 40 with severe oligo- zoospermia were analyzed by PCR for the detection of six sequence- tagged sites: sY84 and sY86 for AZFa, sY127 and sY134 for AZFb, and sY254 and sY255 for AZFc. Microdeletions were detected in 28 patients, including 10 azoospermics and 18 severe oligozoospermics. The patients with azoospermia had 43.4% of their microdeletions in the AZFa region, 8.6% in the AZFb region and 17.4% in the AZFc region. In the severe oligozoospermics, 40% were in the AZFa region, 5% in the AZFb region and 5% in the AZFc region. We conclude that microde- letions can be the cause of idiopathic male infertility, supporting conclu- sions from previous studies.pt_BR
dc.identifier.citationARRUDA, J. T. et al. Y chromosome microdeletions in brazilian fertility clinic patients. Genetics and Molecular Research, Ribeirão Preto, v. 6, n. 2, p. 461-469, 2007.pt_BR
dc.identifier.issne- 1676-5680
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/17953
dc.language.isoengpt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFaculdade de Medicina - FM (RG)pt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectMale infertilitypt_BR
dc.subjectY microdeletionspt_BR
dc.subjectAZFpt_BR
dc.subjectAssisted human reproductionpt_BR
dc.titleY chromosome microdeletions in brazilian fertility clinic patientspt_BR
dc.typeArtigopt_BR

Arquivos

Pacote Original
Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
Artigo - Jalsi Tacon Arruda - 2007.pdf
Tamanho:
395.6 KB
Formato:
Adobe Portable Document Format
Baixar
Licença do Pacote
Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Baixar

Coleções

FM - Artigos publicados em periódicos