Mestrado em Ciências da Saúde (FM)
URI Permanente para esta coleção
Navegar
Navegando Mestrado em Ciências da Saúde (FM) por Por Orientador "ÁVILA, Marcos"
Agora exibindo 1 - 2 de 2
Resultados por página
Opções de Ordenação
Item Avaliação da eficácia e segurança do uso de radioterapia intraocular com estrôncio 90 e bevacizumabe no tratamento de pacientes portadores de degeneração macular relacionada à idade, forma exsudativa(Universidade Federal de Goiás, 2012-03-27) BIANCHI, Lívia Carla de Souza Nassar; ISAAC, David Leonardo Cruvinel; http://lattes.cnpq.br/5474072354473614; ÁVILA, Marcos; http://lattes.cnpq.br/3335187297522447Purpose: To evaluate the efficacy and safety of strontium-90 epimacular brachytherapy combined with intravitreal bevacizumab for treating subfoveal choroidal neovascularization secondary to exudative age-related macular degeneration. Its effects on visual acuity and macular thickness at 36 months of follow up were also studied. Methods: Sixteen patients with predominantly classic, minimally classic and occult choroidal neovascularization were treated with a single 24 Gy dose of radiation during pars plana vitrectomy, associated to two injections of bevacizumab at baseline and one injection at the one-month visit. The patients underwent a complete ophthalmologic examination, which included fluorescein angiography and optical coherence tomography, at the initial visit, every three months during the first year, and every six months during the second and third years of follow up. Results: Of the 16 cases, 2 patients (12.5%) lost more than 15 letters at the end of 36 months, and 3 (18.75%) lost fewer than 15 letters. Among the patients with improved visual acuity, 3 (18.75%) gained less than 15 letters and 8 (50%) gained more than 15 letters at the end of treatment. The mean best corrected visual acuity showed a gain of 16.0 letters at 12 months. After 36 months (n = 16), the mean best corrected visual acuity showed a gain of 10.4 letters. Of the 16 eyes included in the study, six required further therapy. The evaluation of macular thickness showed decreased thickness in 10, among the 16 patients (62.5%). Three eyes (18.75%) had similar values at the beginning and the end of 36 months, and 3 eyes (18.75%) showed increased macular thickness. Conclusion: Epimacular brachytherapy combined with bevacizumab may be considered a possible therapeutic option for choroidal neovascularization in age-related macular degeneration. The procedure was thought to be safe and was well tolerated by the patients. The treatment resulted in anatomical and functional improvements, compatible with currently available therapies.Item Análise das condições de saúde ocular da população atendida no centro de referência em oftalmologia do hospital das clínicas/UFG(Universidade Federal de Goiás, 2011-12-06) ROCHA, Maria Nice Araujo Moraes; ISAAC, David Leonardo Cruvinel; http://lattes.cnpq.br/5474072354473614; ÁVILA, Marcos; http://lattes.cnpq.br/3335187297522447There are few studies of epidemiological research in of Ophthalmology with the population of center-western Brazil. In order to identify the prevalence of the of eye diseases in the region, and specifically in Goiania and Goiás, that impact on blindness and visual impairment, this study analyzed 10,060 records randomly selected from patients seen at the Reference Center for Ophthalmology School of Medicine Federal University of Goiás ((CEROF/UFG), in From April 2009 to March 2010. There was a profile analysis of ocular morbidity in the target population in relation to disease group, acuity, age, sex and region of origin. The study also covered the distribution of queries in the four quarters of the year, elective and urgent, and the degree of visual impairment in the bands visual impairment and blindness. The predominant diseases in elective care in relation to the total sample of 10,060 patients were cataract (7.24%), pterygium (6.77%), allergic conjunctivitis (3.70%), dry eye (3,36%) , diseases of the retina and vitreous (3.23%), strabismus (2.64%) and glaucoma (1.94%). In urgent care were the most prevalent extraocular foreign body (25.5%), infectious conjunctivitis (23.6%), keratitis and and corneal ulcer (11.3%), pterygium and pingueculite (5.3%) and sub conjuntival hemorrhage (4.0%). There was higher prevalence of sex female (63.1%) and ages between 0-14 (26,8%) years and 40 to 49 (20,8%) years in elective consultations. In urgency consultations there was more prevalent of male (64.84%) and ages between 15 and 39 (51.06%) years in clinical urgency. Refractive errors were recorded in 43.08% of queries being found more astigmatism (40.02%) followed by hyperopia (36.54%). Were determined rates of low vision within the parameters of World Health Organization (WHO). The results were compared with other studies in Brazil and abroad, aiming to define the reality of the regional profile of eye health, as an aid to prevention strategies, recovery and treatment through health policies and government's own guidance service studied, the CEROF/UFG. It follows that both elective care and emergency at CEROF/UFG is similar to that found in southern and southeastern Brazil and in most developed countries of the world.